Industrial Technology Research Institute

Bin-Cheng Yao

Chung-Fan Chiou

Yu-Tang Li

Chao-Chi Pan

Cheng-Wei Chu

Shang-Chia Chang

Shan-Peng Pan

Wei-Cheng Chang

A bioassay system is disclosed. The bioassay system may include a plurality of optical detection apparatuses, each of which includes a substrate having a light detector, and a linker site formed over the light detector, the linker site being treated to affix the biomolecule to the linker site. The linker site is proximate to the light detector and is spaced apart from the light detector by a distance of less than or equal to 100 micrometers. The light detector collects light emitted from the biomolecule within a solid angle of greater than or equal to 0.8 SI steridian. The optical detection apparatus may further include an excitation light source formed over the substrate so as to provide a light source for exciting a fluorophore attached to the biomolecule.

Bioassay system including optical detection apparatuses, and method for detecting biomolecules

The present invention relates to a long-stroke nanopositioning device, comprising: a piezoelectric tube; a quartz glass rod; two fixed seats being disposed on the ends of the piezoelectric tube and a piezoelectric actuator. Each of the fixed seats has a base for receiving at least one spring and a plurality of ruby balls. The quartz glass rod is gripped to the fixed seat by the ruby balls of the fixed seat wherein the gripping force is controlled by means of the spring. The piezoelectric actuator applies an input voltage to the piezoelectric tube to cause one end of the piezoelectric tube to have a relative displacement in a direction along the axis of the quartz glass rod. The present invention provides a nanopositioning device capable of long stroke displacements at the nanometer scale by controlling the input voltage of the piezoelectric actuator and the gripping force of the ruby balls.

Long-stroke, high-resolution nanopositioning mechanism

Growing community of inventors

Taipei, Taiwan

Bin-Cheng Yao