University of Arkansas

The Texas A&M University System

The United States of America As Represented by the Secretary of

United States of America, As Represented by the Secretary of Agriculture

University of Guelph

Other

Novozymes A/s

Lynntech, Inc.

The United States of America As Represented by the Department of

Ms Bioscience

Billy M Hargis

Luc Berghman

Lisa Bielke

Sherryll Layton

Olivia B Faulkner

Srichaitanya Shivaramaiah

Young Min Kwon

Walter G Bottje

John R Barta

Neil R Pumford

Guillermo Tellez

Kimberly Cole

Mandy Cox

Marion Morgan

Guillermo Tellez-Isaias

Amanda Wolfenden

John R DeLoach

Michael H Kogut

Ross Wolfenden

Daad Abi-Ghanem

Larry H Stanker

G Duncan Hitchens

Anthony Giletto

K Scott McKenzie

Lisa A Newberry

Ann M Donoghue

Daniel J Donoghue

Stacy E Higgins

Gerardo Nava

Lucas Elzie Graham

Saeed El-Ashram

Kyle Dean Teague

Rita B Moyes

Juan David Latorre

Leona Nicole Calhoun

Edward Deorsey McGruder

Samuel J Rochell

Jacob Lum

Denise Yvette Caldwell

Kellie L Herron

Kelly L Herron

Said El-Ashram

Anita Menconi

Walter Bottje

The present invention providesisolates, as well as probiotic and animal feed compositions comprising said isolates, which may be included in the diet of poultry to improve growth performance with reduced energy diets. Methods of using these compositions to improve nutritional uptake or to reduce the incidence of footpad dermatitis in poultry are also provided.

isolate compositions and methods of using and producing the same

Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.

Compositions and methods of enhancing immune responses toor limitinginfection

Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.

Mucosal adjuvants and delivery systems

Spore forming bacteria and Lactic Acid Bacteria for application in poultry hatcher cabinets to alter the bacterial bloom towards a more beneficial microbiota, positively affecting performance parameters such as mortality, body weight gain and feed conversion ratio throughout production.

Method to reduce microbial bloom in poultry hatchery

Vaccine compositions including a yeast comprising an immunostimulatory polypeptide and optionally an antigenic polypeptide are provided herein. The immunostimulatory polypeptide and the antigenic polypeptide are expressed or displayed on the surface of the yeast vaccine composition. Methods of using the vaccine composition to vaccinate subjects are also provided.

Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same

Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection

Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.

Compositions and methods of enhancing immune responses to enteric pathogens

The present disclosure relates to probiotic compositions, formulations and methods for promoting digestion and improving nutrition in birds, and probiotic compositions and formulations for increasing enzyme production and improving parameters and indications in birds.

Compositions, probiotic formulations and methods to promote digestion and improve nutrition in poultry

Vaccine vectors and methods for enhancing resistance toinfection or for enhancing the immune response toare provided herein. The vaccine vectors include a first polynucleotide which encodes an antigenic polypeptide selected from SEQ ID NO:-or a fragment thereof. The vector may also include an immunostimulatory polypeptide. The methods include administering the vaccine vectors to a subject.

Vaccine and methods to reduce campylobacter infection

Vaccines comprising TRAP polypeptides andvectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.

Compositions and methods of enhancing immune responses to

Provided herein are compositions including a probiotic including at least one strain of live bacteria and a Marek's Disease vaccine. Compositions including a probiotic or a probiotic and a Marek's Disease vaccine may be administered to subjects, including poultry. The compositions may be administered in ovo to increase early lactic acid bacteria in the gastrointestinal tract of the subject, to decrease the gram negative bacteria in the gastrointestinal tract of the subject, to reduce the level ofin the gastrointestinal tract of the subject and to increase the body weight gain of the subject. Also provided are kits including a probiotic and a Marek's Disease vaccine.

Poultry probiotic vaccine compositions and methods of use thereof

Growing community of inventors

College Station, TX, United States of America

Billy M Hargis