W. L. Gore & Associates, Inc.

Edwards Lifesciences Corporation

Bill R Finney

Cody L Hartman

David J Arcaro

William C Bruchman

Paul D Gassler

Dustin V Dienno

Logan R Hagaman

Peter J Walsh

Roy Manygoats, Jr

Russell L Jacoby

Joshua C Haarer

Benjamin A Smith

Edwin W Field

Stephen M Probert

Jason T Alger

Olga Baykova

Kevin J Derryberry

Andrew P Hilton

Roy Manygoats

Stephen Probert

Aspects of the disclosure relate to prosthetic valves having a frame, a frame cover, and a leaflet construct. Some aspects are directed to a diametric taper for the prosthetic valve for achieving enhanced performance of the prosthetic valve under operational conditions, enhanced compressibility and delivery characteristics, and other additional or alternative advantages. Other aspects are directed toward unique assembly and attachment methods for securing leaflet constructs to support structures. Other aspects are directed toward features for interacting with transcatheter delivery systems. Still other aspects are directed to such apparatuses, systems, and methods for valve replacement, such as cardiac valve replacement.

Prosthetic valve with expandable frame and associated systems and methods

Thin, biocompatible, high-strength, composite materials are disclosed that are suitable for use in a prosthetic valve for regulating blood flow direction. In one aspect, the leaflet material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a prosthetic heart valve leaflet. The leaflet material includes a coherent single layer and an elastomer, wherein the elastomer is present in the pores of the porous coherent single layer.

Coherent single layer high strength synthetic polymer composites for prosthetic valves

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Flagstaff, AZ, United States of America

Bill R Finney