Metanomics Gmbh

Ruprecht-karls-universitat Heidelberg

Charité – Universitätsmedizin Berlin

Metanomics Health Gmbh

Bianca Bethan

Jan C Wiemer

Edgar Leibold

Kristina Busch

Martijn Gipmans

Jochen Spranger

Thomas Bobbert

Andreas Friedrich Hermann Pfeiffer

Thomas Ehrhardt

Ralf Looser

Tilmann B Walk

Hugo Katus

Michael Manfred Herold

Martin Kluttig

Jens Fuhrmann

Alexandre Prokoudine

Bennard Van Ravenzwaay

Werner Mellert

Georgia Coelho Palermo Cunha

Beate Kamlage

Regina Reszka

Norbert Frey

Oliver Schmitz

Tanja Weis

Jürgen Kastler

Johanna Wolf

Gerhard Krennrich

Glen Kristiansen

Klaus Jung

Carsten Stephan

Michael Lein

Johanna Sigl Geb Wolf

The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject and a method for monitoring progression or regression of heart failure in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.

Means and methods for diagnosing and monitoring heart failure in a subject

The present invention relates to a method for diagnosing diabetes or a predisposition thereof, comprising determining at least one metabolite in a test sample of a subject suspected to suffer from diabetes or to have a predisposition therefor and comparing the metabolite to a reference to diagnose diabetes or a predisposition therefor. The present invention further encompasses a collection of metabolites, a data collection comprising characteristic values of metabolites and a storage medium comprising the data collection. The present invention also relates to a system comprising methods or devices for comparing characteristic values of metabolites of a sample operatively linked to a data storage medium. The present invention also encompasses diagnostic methods or devices comprising at least one metabolite and use of the metabolite for the manufacture of diagnostic methods and devices for diagnosing diabetes; and a method for identifying diabetes-related metabolites.

Means and method for diagnosing diabetes

The present invention relates to a method for diagnosing a predisposition for diabetes, comprising determining a metabolite in a test sample of a subject suspected to have a predisposition for diabetes and comparing the metabolite to a reference to diagnose the, predisposition for diabetes. Moreover, the present invention encompasses a collection of metabolites, a data collection comprising characteristic values of metabolites and a storage medium comprising the data collection. The present invention also relates to a system comprising methods or devices for comparing characteristic values of metabolites of a sample operatively linked to a data storage medium. Additionally, diagnostic methods or devices comprising a metabolite and its use for manufacture of the diagnostic method or device for diagnosing a predisposition for diabetes are provided, along with a method for identifying diabetes-related metabolites.

Means and method for predicting diabetes

A method for analyzing a test sample is disclosed, the test sample comprising at least one compound. A test sample comprising at least one compound is provided. Next, the at least one compound in the test sample is determined, thereby generating raw results. The generated raw results are analyzed, wherein the analysis of the test sample is accompanied by an analysis of at least one reference sample. The test sample and the reference sample are analyzed in an identical sequence in each step of the method. A system for carrying out the method is also disclosed.

System and method for analyzing a sample using chromatography coupled mass spectrometry

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Berlin, Germany

Bianca Bethan