Eastman Chemical Company

Other

Bhaskar Krishna Arumugam

Steven Thomas Perri

Nick Allen Collins

Chester Wayne Sink

Larry Wayne Blair

Brendan William Boyd

Michael R Cushman

Charles Michael Buchanan

Joseph Robert Zoeller

Michael E Burns

Robert Richard Dykstra

Norma Lindsey Buchanan

Jeffrey Scott Dupont

Matthew Davie Wood

John C Hubbs

Shane Kipley Kirk

Ruairi Seosamh O'Meadhra

George Chester Zima

Kevin John Fontenot

Michael Charles Shelton

Elaine Beatrice Mackenzie

Robert Lee Eagan

Mark Robert Shelton

John Steele Debenham

Thomas Hugh Williams

Gary Paul Lutz

George William Tindall

Jarvey Eugene Felty, Jr

Jeffery Earl Grant Powell

Michael Visneski

Eddie Joseph Eckart

David Anthony Larkin

John K Sanders

Larry R Lingerfelt, Jr

Transito Lynne Macias

Jeffrey Earl Grant Powell

Tony Lee Sander

Jeffrey William Green

Dimmick Lee Bymaster

Disclosed is a process for dewatering an organic compound other than a carboxylic acid using a simulated moving bed (SMB) containing a solid with different absorptivities for water and the organic compound. The organic compound is fed into the SMB as an aqueous solution and desorbed with a desorbent other than water. The process is particularly useful for dewatering organic compounds produced by fermentation, biomass extraction, biocatalytic, and enzymatic processes.

Dewatering process

The present invention comprises the use of sulfite additives to reduce discoloration of L-ascorbic acid produced from acid or aqueous solutions of 2-keto-L-gulonic acid. In one aspect, the present invention comprises a continuous process for producing L-ascorbic acid from an aqueous solution of 2-keto-L-gulonic acid. The use of sulfite additives reduces product stream color and improves product recovery by binding to high molecular weight reaction by-products. In a continuous process, the reaction stream is separated from residual sulfite and sulfite-bound by-products to produce a product stream enriched in aqueous ascorbic acid for recovery, and an enriched 2-keto-L-gulonic acid stream which is recycled to the reactor. The in situ use of sulfite additives during the reaction increases the overall yield of L-ascorbic acid, with no loss in selectivity of the synthesis.

Process for producing ascorbic acid

Process for the recovery of organic acids from aqueous solutions

The present invention provides methods and an apparatus for the manufacture of an L-ascorbic acid product in high yield by direct conversion of an aqueous solution containing 2-keto-L-gulonic acid by contact with an acid catalyst or under thermal self-catalyzed conditions at a conversion level that maximizes the formation of L-ascorbic acid and minimizes decomposition of the L-ascorbic acid thus formed. The separation process for L-ascorbic acid and KLG is operated in such a way that an efficient separation process allows the majority of the KLG to be recycled for further conversion. The product stream from the separation process is then subjected to a recovery step to obtain crystalline L-ascorbic acid product.

Continuous process for producing L-ascorbic acid

The invention relates to a process for purifying and decolorizing a phenyl ester salt. The process combines a phenyl ester salt with a solvent to form a mixture and then stirs the mixture to form a slurry. The phenyl ester salt is substantially insoluble in this solvent. The process then collects the phenyl ester salt from the slurry. The collected phenyl ester salt may then be optionally dried or recrystallized. The collected phenyl ester salt is dissolved in a solvent to form a solution. The solution is decolorized and then spray dried to form a powder of the phenyl ester salt. As a result of the process the phenyl ester salt powder has a higher purity and an improved color as compared to the starting phenyl ester salt.

Purification of phenyl ester salts

Disclosed is a process wherein a solution of a carboxylic acid in a first solvent and an alcohol are fed to a simulated moving bed reactor (SMBR) containing a solid(s) to produce a first stream comprising a solution of an ester of the carboxylic acid and the alcohol and a second stream comprising the first solvent. The solid(s) present in the SMBR facilitates the esterification reaction and the separation of the first solvent from the carboxylic acid. The process is particularly valuable for the preparation of an alkanol solution of an alkyl 2-keto-L-gulonate ester (AKLG) from an aqueous fermentation broth containing dissolved 2-keto-L-gulonic acid (KLG) by feeding the fermentation broth and an alkanol to a simulated moving bed reactor which contains a solid acidic esterification catalyst to produce a stream comprising an alkanol solution of an ALKG. The alkanol solution of an ALKG may be used directly to convert the ALKG to ascorbic acid (Vitamin C).

Preparation of esters of carboxylic acids

The present invention is a process for the preparation of ascorbic acid using a simulated moving bed (SMB) reactor system to accomplish the simultaneous conversion of KLG or a derivative of KLG to ascorbic acid and the separation of reaction products. The SMB reactor contains a solid or mixture of solids effective for catalyzing the reaction of KLG or its derivative and for separating the reactions products by selective adsorption of at least one product. In a general embodiment, this process involves (1) feeding a solution of KLG or a derivative thereof in a first solvent and a desorbent which is miscible with the first solvent, to a simulated moving bed reactor; (2) reacting the KLG or the KLG derivative to form ascorbic acid; and (3) removing from the simulated moving bed reactor (i) a first liquid stream comprising a solution of ascorbic acid in the desorbent and the first solvent (ii) a second liquid stream comprising the first solvent and the desorbent.

Process for the preparation of ascorbic acid

In one aspect, the invention provides methods of obtaining at least one monosaccharide from corn fiber the method comprises the steps of: (a) heating an aqueous mixture of corn fiber and a liquid; (b) contacting the mixture of step (a) with a protease enzyme, thereby providing a proteolyzed corn fiber and a liquid; (c) separating the liquid from the proteolyzed corn fiber; (d) contacting the proteolyzed corn fiber at least once with an alkaline extractant, thereby providing an insoluble cellulose material and a liquid comprising arabinoxylan; (e) separating the insoluble cellulose material from the liquid comprising arabinoxylan; (f) reducing the volume of the liquid comprising arabinoxylan by removing excess alkaline extractant, thereby providing a concentrated liquid comprising from about 10 to about 50% solids, wherein the solids comprise arabinoxylan; and (g) hydrolyzing the arabinoxylan from step (f) in the presence of a catalyst and a solvent, thereby providing a mixture comprising at least one monosaccharide. In a further aspect, the invention pertains to methods of separating the monosaccharides obtained from corn fiber according to the methods disclosed herein.

Corn fiber for the production of advanced chemicals and materials: separation of monosaccharides and methods thereof

Growing community of inventors

Kingsport, TN, United States of America

Bhaskar Krishna Arumugam