Pfizer Corporation

Cultor Corporation

Bharat K Shah

Donald B Guzek

Russell J Hausman

Constantine Sklavounos

Sulfoalkyl ether cyclodextrins are produced by a process of treating an unsubstituted cyclodextrin starting material with an alkyl sultone in the presence of a base. The base is added in a stepwise, pH controlled manner so that substantially the entire initial charge of cyclodextrin starting material is at least partially reacted. Additional base is then added to complete the reaction, and residual alkyl suftone is destroyed. The product advantageously contains low levels of both residual cyclodextrin and residual alkyl sultone.

Process for making a cyclodextrin

An improved, water-soluble polydextrose containing 0.3 mol % or less of bound citric acid, a process therefor, and foods containing same.

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Terre Haute, IN, United States of America

Bharat K Shah