Case Western Reserve University

Bhairav Bipin Mehta

Mark A Griswold

Simone Coppo

Nicole Seiberlich

Vikas Gulani

Michael Twieg

Yong Chen

Systems and methods are provided for acquiring imaging data from one or more resonance species that simultaneously produce individual magnetic resonance signals in a plurality of different slices. The data is acquired by simultaneously exciting, using a pTX RF coil array, a plurality of different slices such that at least some of the plurality of different slices are excited by transmitting RF energy from a subset of transmit channels in the pTX RF coil array. The method also includes comparing the data to a dictionary of signal evolutions to determine quantitative values for two or more parameters of the resonant species based, at least in part, on matching the data to a set of known signal evolutions stored in the dictionary. The method includes producing an image for each of the plurality of different slice locations, at least in part, on the quantitative values.

System and method for simultaneous multi-slice magnetic resonance fingerprinting imaging using a parallel transmit radio frequency coil array

A system and method for generating quantitative images of a subject using a nuclear magnetic resonance system. The method includes performing a navigator module to acquire navigator data, and performing an acquisition module during free breathing of the subject to acquire NMR data from the subject that contains one or more resonant species that simultaneously produce individual NMR signals in response to the acquisition module. The above steps are repeated to acquire data from a plurality of partitions across the volume. The navigator data is analyzed to determine if the NMR data meets a predetermined condition and if not, the above steps are repeated for at least an affected partition corresponding to NMR data that did not meet the predetermined condition. The NMR data is compared to a dictionary of signal evolutions to determine quantitative values for two or more parameters of the resonant species in the volume.

Systems and methods for free-breathing three-dimensional magnetic resonance fingerprinting

Methods for magnetic resonance fingerprinting ('MRF') that are more robust to patient motion than conventional MRF techniques are described. The methods described in the present disclosure provide an image reconstruction algorithm for MRF that decreases the motion sensitivity of MRF.

System and method for motion insensitive magnetic resonance fingerprinting

A system and method is provided for performing a magnetic resonance fingerprinting (MRF) study in the face of inhomogeneous magnetic fields. The process includes performing a balanced steady-state free precession (bSSFP) pulse sequence multiple times to acquire a multiple MRF datasets from at region of interest (ROI) in a subject, wherein performing the multiple bSSFP pulse sequences includes cycling through multiple phase patterns that differ across the multiple times. The process also includes comparing the multiple MRF datasets with a MRF dictionary to determine at least one tissue property indicated by each of the multiple MRF datasets, producing an aggregated indication of the at least one tissue property, and producing at least one map of the at least one tissue property using the aggregated indication of the at least one tissue property.

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Cleveland, OH, United States of America

Bhairav Bipin Mehta