Smithkline Beckman Corporation

Smithkline Corporation

Betty A Bowie

Marcia C Shearer

David J Newman

Robert D Sitrin

Joseph F Pagano

Joseph R Valenta

Thomas O Lindsey

Richard D Hedde

A novel antibiotic complex of 'vancomycin-like' antibiotics, AAD 216 complex, is produced by the cultivation of a fermentation broth containing Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The AAD 216 complex and its major bioactive components; AAD 216A, AAD 216B, and AAD 216C exhibit antibiotic activity and growth promotant activity.

Antibiotics produced by Kibdelosporangium aridum Shearer gen. nov., sp.

Pure cultures of Kibdelsporangium aridum Shearer gen. nov., sp. nov.

A novel antibiotic complex of 'Vancomycin-like' antibiotics, AAD 216 complex, is produced by the cultivation of a fermentation broth containing Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The AAD 216 complex and its major bioactive components; AAD 216A, AAD 216B, and AAD 216C exhibit antibiotic activity and growth promotant activity.

Antibiotics produced by Kibdelosporangium aridum shearer

Stable oxidase reagent solutions containing N,N,N',N'-tetramethyl-p-phenylenediamine or N,N-dimethyl-p-phenylenediamine for determining the presence of oxidase in microbial colonies.

Stable oxidase reagent solutions

A device for making a culture of carbon dioxide (CO.sub.2) requiring organisms has an elongated member supporting a culture medium in a container having an open end which is adapted to be closed by sealing means. A CO.sub.2 tablet is secured to the elongated member between the culture medium and the open end of the container.

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Havertown, PA, United States of America

Betty A Bowie