Georgia Tech Research Corporation

Degussa Aktiengesellschaft

Dow Global Technolgoies LLC

Rohm and Haas Company

Roche Diagnostics Operations, Inc.

Emory University

Georgia State University Research Foundation, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Bettina Bommarius

Werner Hummel

Andreas Sebastian Bommarius

Christopher W Jones

Rainer Mueller

Paul Edward Doll

Sudhakar Balijepalli

John Anderson Roper, Iii

Johann-Peter Thalhofer

Werner Hoelke

Frank Geipel

Stephan Glaser

Thomas Kirschbaum

Hellmut Eckstein

Adam Holewinski

Jonathan Taejoo Park

Vaijayanthi Thangavel

Christopher R Murdock

John M Robbins

Akihiro Nomura

Giovanni Gadda

Jun-Ichiro Hirano

Michael Justin Abrahamson

Andreas Sebastain Bommarius

A coating for conversion of formaldehyde to carbon dioxide includes an alcohol/aldehyde oxidase and a formate oxidase immobilized on a solid particulate support; and a latex binder.

Coating for aldehyde remediation and method of making

Non-naturally occurring amine dehydrogenases (AmDH) and methods of use thereof the produce chiral amines are disclosed. The AmDH are variants of amino acid dehydrogenases. AmDH based on phenylalanine, leucine, and valine scaffolds are provided. The AmDH typically have one, two, three, four, or more amino acid alterations relative to the scaffold. The alterations to the scaffold result in an enzyme that accepts the analogous ketone, such as methyl isobutyl ketone (MIBK), instead of the wild-type &#x3b1;-keto acid. Chimeric AmDH are also disclosed. The chimeras are fusion proteins that include a substrate binding domain from a first AmDH and a cofactor binding domain from a second AmDH. In a preferred embodiment, one of the domains is from a PheDH-based AmDH and one of the domains is from a LeuDH-based AmDH.

Engineered amine dehydrogenases and methods of use thereof

The present disclosure relates generally to bacterial NADH oxidases and, more particularly, to novel NADH oxidases obtained from, and derivatives thereof that demonstrate enzymatic activity for NADH, NADPH, or both NADH and NADPH. The compositions comprising an NADH oxidase obtained fromor derivatives thereof include: isolated enzymes; recombinantly produced enzymes and derivatives thereof, as well as catalytically active portions thereof; nucleic acids encoding an NADH oxidase obtained from, derivatives thereof, and portions thereof. The methods of the present invention include isolation of NADH oxidases obtained from, derivatives thereof, and portions thereof, and methods for enzymatic reactions comprising NADH oxidase obtained from, including the production of enantiomer-enriched organic compounds.

Compositions and methods for using NADH oxidases

The present invention is directed to a new NADH oxidase from, nucleic acids encoding the NADH oxidase, methods of producing the NADH oxidase, as well as there use in producing improved NADH oxidase enzymes and for producing chrial enantiomer-enriched organic compounds, such as alcohols and/or amino acids.

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The present invention is directed to a new NADH oxidase from Lactobacillus, nucleic acids encoding the NADH oxidase, methods of producing the NADH oxidase, as well as there use in producing improved NADH oxidase enzymes and for producing chrial enantiomer-enriched organic compounds, such as alcohols and/or amino acids.

NADH oxidase from lactobacillus

This invention involves a process for selecting and producing eukaryotic alkaline phosphatase in yeast. Yeast cells are subjected to multiple transformations using a vector comprising a first resistance marker gene and the alkaline phosphatase gene. Those strains that grow in media containing the first resistance marker are further transformed using a vector comprising a second selection marker gene and the alkaline phosphatase gene. Transformants that grow in media containing the second selection marker are selected for expressing the eukaryotic alkaline phosphatase.

Expression of alkaline phosphatase in yeast

Growing community of inventors

Atlanta, GA, United States of America

Bettina Bommarius