Ligand Pharmaceuticals, Inc.

Agenus Inc.

Beth Wensley

Olga Ignatovich

Benjamin Maxime Morin

Zahra Jawad

Veronica Franciszka Ilkow

Dhan Sidhartha Chand

Emmanuel Cyrille Pascal Briend

K Mark Bushell

Nicola Anne Ramsay

Spencer Campbell

POLYNUCLEOTIDE ENCODING ANTI-TIGIT AND ANTI-CD96 ANTIBODIES

The instant disclosure provides multispecific molecules that specifically bind to CD96 (e.g., human CD96) and/or TIGIT (e.g., human TIGIT) and isolated antibodies that specifically bind to TIGIT (e.g., human TIGIT). Also provided are pharmaceutical compositions comprising these multispecific molecules and antibodies, nucleic acids encoding these multispecific molecules and antibodies, expression vectors and host cells for making these multispecific molecules and antibodies, and methods of treating a subject using these multispecific molecules and antibodies.

Anti-TIGIT and anti-CD96 antibodies

Growing community of inventors

Lexington, MA, United States of America

Beth Wensley