Merck Patent Gmbh

Merck Patent Gesellschaft MIT Beschrankter Haftung

Other

Ortho-mcneil Pharmaceutical Corp.

Merck Patent Gesellschaft

3-dimensional Pharmaceuticals, Inc.

Bertram Cezanne

Werner Mederski

Christos Tsaklakidis

Dieter Dorsch

Johannes Gleitz

Christopher Barnes

Gerhard Barnickel

Norbert Beier

Rolf Gericke

Richard M Soll

Mark R Player

Markus Klein

Daljit Singh Dhanoa

James M Rinker

Sabine Bernotat-Danielowski

Christoph Van Amsterdam

Bao-Ping Zhao

Hanns Wurziger

Hartmut Greiner

Ralf M Devant

James Vickers

Hans-Peter Buchstaller

Michael Wolf

Gerd Bartoszyk

Hans-Michael Eggenweiler

Guenter Hoelzemann

Christiane Amendt

Lars Thore Burgdorf

Guido Melzer

Ulrich Graedler

Henning B&ouml;ttcher

Maria Devant, Legal Representative

Edward Jaeger

Wrner Mederski

Edward Jaegar

Novel compounds of the formula I, in which X, Y, R, R', R, R, R, R, R, R, R, R, R, Rand n have the meanings indicated in Patent Claim, are suitable as antidiabetics 

3-aminoimidazo [1,2-A] pyridine derivatives as SGLT inhibitors

Novel compounds of the formula (I), in which W, T, R, R, R, R, Rand Rhave the meanings indicated in Patent Claim (), are suitable as antidiabetics. 

3-aminoimidazo 1,2-A pyridine derivatives having an SGLT1- and SGLT2-inhibiting action for the treatment of type 1 and type 2 diabetes

Novel compounds of the formula (I), in which D, E, G, W, X, Y, T, Rand Rare as defined in Patent Claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors. 

Carbonyl compounds

Novel compounds of the formula I (I), in which R, R, R, R, R, R, R, R, R, R, R, R, R, R, Q, W, X and Z have the meanings indicated in Patent Claimare suitable as antidiabetics.

Benzimidazole derivatives

Novel triazole derivatives are inhibitors of TGF-beta receptor I kinase, and can be employed, inter alia, for the treatment of tumours.

Triazole derivatives

Novel adenine derivatives of the formula (I), in which R, R, R, X and Y have the meanings indicated in Claim, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role. 

Adenine derivatives

Novel compounds of the formula (I) in which D, E, Q, T, X, Y, Z, Z', R, Rand Rhave the meanings indicated, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.

Piperidinyl compounds

Novel compounds of the formula (I), in which D, E, G, W, X, Y, T, Rand Rare as defined in Patent Claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours. 

Novel compounds of the formula (I), in which D, W, X, Y, T and Rare as defined in Patent Claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.

Phenyl derivatives as factor XA inhibitors

4-amino-quinazolines

Novel compounds of the formula (I) in which Het, R, Rand Rhave the meaning indicated in Patent claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors. 

Aroylsemicarbazide derivatives against thromboembolic diseases

Novel compounds of the formula (I), in which R, R, R, R, X, X' and Y have the meaning indicated in Patent Claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors. 

Prolinylarylacetamides

The invention relates to a method for production of compounds of formula (I), where X has the meaning given in claimand precursors for the same.

Process for the production of N-arylmorpholinones

Novel compounds of the formula (I), in which R, R, R, Rand Rhave the meaning indicated in Patent Claim, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours. 

Prolinyl derivatives for the treatment of thrombosis

Novel compounds of the formula (I) in which R, D, X, W, Y and T have the meaning indicated in Patent Claim (1), e.g. (II), are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors. 

Growing community of inventors

Mörfelden-Walldorf, Germany

Bertram Cezanne