Sartorius Stedim Biotech Gmbh

Bernward Husemann

Wolfgang Kahlert

Simon Topp-Manske

Marco Leupold

Reiner Seitz

Gerhard Greller

Ute Husemann

Sebastien Chaussin

Bjoern Nickel

Heinz-Ruediger Keitel

Christian Grimm

Thomas Regen

Rainer Salzmann

Stefan Zeuch

Christian Zahnow

Matthias Hielscher

Davy De Wilde

Ralf Hartmann

Bjorn Nickel

Heinz-Rüdiger Keitel

A container () of a bioreactor (a,) has a container interior () designed for being filled with a medium () including a photoreactive material, and designed for at least partially triggering a photochemical reaction of the photoreactive material. The container () has at least one illuminant receiving pouch () that is at least partially transparent for an electromagnetic radiation (), and that is arranged on a illuminant opening () within the container interior () and is designed to receive at least one illuminant () from an outer side (A) through the illuminant opening (). The illuminant at least partially irradiates the medium () such that the photochemical reaction of the photoreactive material can be triggered by electromagnetic radiation () emitted by the illuminant and the illuminant is isolated in relation to the medium () by the illuminant receiving pouch ().

Illumination for a photobioreactor

A bioreactor () includes a receiving container () for receiving a disposable bag (). A bottom surface () of the receiving container () is designed to support the disposable bag () in the receiving container (). An outlet opening () is formed in the bottom surface () and tapers down with respect to the ground for receiving a drain port () of the disposable bag (). The drain port is complementary to the outlet opening ().

Bioreactor system and method

A probe holder (), for positioning at least one probe () such that the probe () at least partially engages in a system () for biotechnological uses, comprises a holder base () for positioning the probe holder () on the system () for biotechnological uses and at least one probe positioning means (), which is designed to position the at least one probe () such that the probe () extends in a probe extension direction (S; S, S, S, S). The probe positioning means () is positioned on the holder base () such that the position of the probe () is variably adjustable in a probe extension direction (S; S, S, S, S).

Probe holder and method for positioning a probe

A system for receiving a disposable bag () has a receiving container () with a container interior for receiving the disposable bag () and a temperature-control hollow wall () that at least partially surrounds the container interior of the receiving container (). A temperature-control unit controls the temperature of the container interior by will a temperature-control medium arranged in the temperature-control hollow wall () at a maximum pressure of about 1 bar.

System, device and method for receiving a disposable bag

A container () has a flexible wall () and at least one emptying tube () that projects through a wall aperture () into the container interior () surrounded by the flexible wall (). The free end () of the emptying tube has an emptying opening () that can be set in position vertically to different emptying heights (). The container () is distinguished in that an adapter piece (), in which the emptying tube () is held in a longitudinally displaceable manner, is arranged in the wall aperture and in that a portion of the emptying tube () is surrounded by a flexible sheath () that is connected at a first end () to the emptying tube () and at its second end (), which is remote from the first end (), to the wall () or the adapter piece ().

Container with a flexible wall

A container () has flexible walls surrounding a container interior (). At least one electrical sensor (&#x2033;&#x2033;) projects into the container interior () and has at least first and second electrically conductive plates ('&#x2033;) for determining the conductivity or impedance of a medium that surrounds the plates (&#x2032;&#x2033;). The plates (&#x2032;&#x2033;) are connected via connecting lines () to a control and regulating unit () outside the container interior (). At least the first plate (&#x2032;) is on a closed free end of a sheathing (&#x2033;&#x2033;) and has a contact area exposed to the surrounding medium. The sheathing (&#x2033;&#x2033;) is a flexible hose () or bellows (&#x2033;&#x2033;) through which the electrical connecting line () of the plate (&#x2032;&#x2033;) is routed.

Container with flexible walls

A system () is provided for switching over exhaust air of a bioreactor () that has a disposable container (). The system () has at least two exhaust air ducts () connecting the disposable container () to exhaust air filters ('). A valve () is disposed in at least one of the at least two exhaust air ducts () and enables the associated exhaust air filter (&#x2032;) to be freed.

System for switching over the exhaust air of a bioreactor

A receptacle has a wall defining a receptacle interior and a shaft housing for guiding a shaft through the wall into the receptacle interior. The shaft housing defines an annular cap with spaced apart inner and outer walls connected by an inner end face facing the receptacle interior. A shaft guide part has an end facing the receptacle interior and an outer surface that defines a gap relative to the inner wall of the shaft housing. The shaft guide part has an annular wall spaced apart from and parallel to its outer surface. The annular wall extends over the free end of the inner wall of the shaft housing and is sealed to the inner and outer walls of the shaft housing by at least one seal each. The shaft guide part is mounted in the shaft housing by a radial ball bearing and by an axial ball bearing.

Receptacle comprising a shaft housing

A transport device for a container has a base, a vertical member extending up from the base and a complementary handling unit extending from an end of the vertical member spaced from the base. The complementary handling unit is configured for releasably engaging a container, such as a bioreactor container, so that the container can be transported to a holding device.

Transport device for a container

One aspect relates to a container for inserting into a holding device, comprising: a wall that is flexible at least in some areas, which wall is squashed, at least in some areas, in a transport condition in a direction opposite to a stretching direction; a handling unit connected to the wall, which is designed to come into engagement with a complementary handling unit of a transport device; a securing unit which in a transport condition hinders stretching of the wall of the bioreactor container along the stretching direction, wherein the container can, when the securing unit is released, be extended at least in some areas along the stretching direction, as well as a transport device, a use and a method.

Growing community of inventors

Goettingen, Germany

Bernward Husemann