Forschungszentrum Julich Gmbh

Intercell Ag

Degussa Aktiengesellschaft

Evonik Degussa Gmbh

Bernhard Eikmanns

Andreas Meinke

Hermann Sahm

Dieter J Reinscheid

Axel Schubert

Brigitte Bathe

Georg Thierbach

Volker F Wendisch

Verena Engels

Heike Gutekunst

Bastian Blombach

Lothar Eggeling

Bettina Mockel

Bettina M&ouml;ckel

Yvonne Tilg

Christian Riedel

Dieter Reinscheid

Heike Boisvert

The invention relates to a recombinant coryneform bacterium which secretes an organic chemical compound and in which the sugR gene which codes for a polypeptide having the activity of an SugR regulator has been attenuated. The invention further relates to a processes for using this bacterium for the fermentative preparation of organic chemical compounds.

Process for the fermentative preparation of organic chemical compounds using Coryneform bacteria in which the sugR gene is present in attenuated form

The present invention is related to nucleic acids coding for adhesion factors of group B, adhesion factors of group Band uses thereof. More particularly, the present invention is related to a polypeptide being such adhesion factors and comprising an amino acid sequence, whereby the amino acid sequence is selected from the group comprising SEQ ID NO 11 to SEQ ID NO 20, and the use of such polypeptide for the manufacture of a vaccine.

Nucleic acids coding for adhesion factor of group B streptococcus, adhesion factors of group B streptococcus and further uses thereof

Process for the fermentative preparation of organic chemical compounds using coryneform bacteria in which the SugR gene is present in attenuated form

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The invention relates to isolated nucleotide sequences from Coryneform bacteria which code for the pck gene encoding the enzyme phosphoenol pyruvate carboxykinase (PEP carboxykinase). The invention also relates a process for the fermentative preparation of L-amino acids, in particular L-lysine, L-threonine, and L-glutamate by attenuation of the pck gene.

Nucleotide sequences which code for the pck gene

The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.

Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene

DNA which regulates gene expression in coryneform bacteria

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Ulm, Germany

Bernhard Eikmanns