Roche Diagnostics Operations, Inc.

Boehringer Mannheim Gmbh

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Bernhard Eckert

Johann Karl

Michael Gerg

Julia Riedlinger

Martin Kaufmann

Klaus Hirzel

Lars Hillringhaus

Marcus-Rene Lisy

Hans-Peter Josel

Helmut Lenz

Elke Faatz

Barbara Upmeier

Martin Burri

Beatus Ofenloch-Hahnle

Norbert Franken

Dieter Roessler

Sascha Antoni

Andreas Woeste

Elena Pfaffenrot

Magdelena Swiatek-de-Lange

Magdelena Swiatek-de Lange

Werner Doeppen

Peter Heiss

Sandra Rutz

The present disclosure relates to specific binding agents binding to different PIVKA-II forms as compared to antibodies known so far in the art. The present disclosure also relates to methods of using the specific binding agents to detect the presence of PIVKA-II.

Binding agent and assay for PIVKA

A test management system is presented. The system comprises an analyzer to perform tests a sample according to a first set of instructions, a manager module connected to the analyzer, and a first order interface connected to the manager module. The manager module directs activity of the analyzer according to a second set of instructions. The first order interface receives an order for a first analytical test and a second analytical test and transmits the order to the manager module. If the order is for the first analytical test, the test manager module forwards the order directly to the analyzer and the sample is analyzed by the analyzer according to the first set of instructions. If the order is for the second analytical test, the manager module handles the order according to the second set of instructions and generates and transmits secondary test requests to the analyzer.

Analytical test management system and method

The present invention concerns a method for the determination of an analyte in a sample liquid using a metal complex capable of luminescence as an analyte-specific marker group for the production of a measuring signal in which an unspecific metal complex is additionally added as an interference elimination reagent which has a structure that is chemically related to the marker group.

Interference elimination reagent for the determination of an analyte

Growing community of inventors

Weilheim, Germany

Bernhard Eckert