Commissariat a L'energie Atomique

Centre National De La Recherche Scientifique

Ipsen Pharma S.a.s.

Pierre Fabre Medicament

Le Centre National De Recherche Scientifique (cnrs)

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Bernard Rousseau

Roland Cherif-Cheikh

Jean-Christophe Cintrat

Franck Artzner

Céline Valery

Marie-Thérèse Paternostre

Eric Marechal

Stéphane Roux

Eric Doris

Nadia Saidani

Cyrille Botte

Paul Hellier

Melinda Ligeti

Emerson Giovanelli

Sébastien Comesse

Lionel Moisan

Roman Lopez

Nicolas Fay

Hélène Hardre

Michael Deligny

Anne-Laure Bonneau

Christophe Tarabout

Maarten Ijsselstijn

Roland Cherif-cheikh

The present invention relates to novel octapeptide compounds of general formula (I): H-2-Nal-cyclo(Cys-Tyr-AA-Lys-Val-Cys)-Thr-NH. Since these products have a good affinity for certain somatostatin receptor subtypes, they are particularly advantageous for treating pathological states or diseases in which one (or more) somatostatin receptor(s) is (are) involved. These compounds furthermore have physiochemical properties that make it possible to envisage them in diverse solutions for the formulation of medicaments, for example as a pharmaceutically acceptable carrier. The invention also relates to pharmaceutical compositions containing said products and to the use thereof for the preparation of a medicament.

Octapeptide compounds derived from somatostatin and the therapeutic use thereof

The present invention relates to novel octapeptide compounds of general formula (I),R-AA-cyclo(AA-Tyr-D-Trp-AA-Val-Cys)-Thr-NH&#x2003;&#x2003;(I)As these products have a good affinity for certain sub-types of somatostatin receptors, they are particularly useful for treating the pathological states or diseases in which one (or more) of the somatostatin receptors is (are) involved. The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.

Octapeptide compounds and therapeutic use thereof

The invention relates to the use of compounds having a monogalactosyldiacylglycerol (MGDG) synthase inhibitory activity as herbicide or algaecide, and to herbicide and algaecide compositions containing at least one of these compounds.

Compounds having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions

The fluorinated derivatives of catharanthine according to the invention respond to the general formula I: in which:

[object Object]

Growing community of inventors

Levallois-Perret, France

Bernard Rousseau