Alliance Pharmaceutical Corp.

Universite D'avignon Et Des Pays Du Vaucluse

Ts Pharma

Centre National De La Recherche Scientifique

Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic

University D'avignon Et Des Pays De Vaucluse

Bernard Pucci

Jean G Riess

Leila Zarif

Andre A Pavia

Camille Guedj

Grégory Durand

Ange Polidori

Olivier Braun

Paul Mallo

Guy Tabacchi

Jean-Pierre Salles

Jean-Luc Popot

Fabrice Giusti

Gregory Durand

Sharma Kshatrapati Shivaji

Paola Bazzacco

Kshatrapati Shivaji Sharma

The invention relates to an amphiphilic polymer comprising at least 75% of amphiphilic monomers of formula (I), the average molar mass of the polymer being between 800 and 100 000, and also water-soluble complexes between the polymer according to the invention and a hydrophobic or amphiphilic compound, in particular a membrane protein, a concentrated aqueous solution of one or more such complex(es), a product comprising one or more such complex(es) attached to a substrate by means of the polymer according to the invention, and various uses of these products.

Polymers comprising a majority of amphiphilic monomers intended for trapping and manipulating membrane proteins

Compounds derived from &#x3b1;-C-phenyl-N-tert-butylnitrone, a process for the preparation thereof and use thereof for the preparation of medicaments for use in preventing or treating oxidative stress-related diseases.

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Novel compounds, derivatives of &#x3b1;-C-phenyl N-tert-butyl nitrone, a method for production and use thereof for the preparation of medicaments for the prevention of treatment of diseases related to oxidative stress.

The invention concerns a linear or crosslinked polymer, characterized in that it is obtainable either by copolymerizing N-[2-hydroxy-1,1-bis(hydroxymethyl)-ethyl]-propenamide, or by copolymerizing N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl][-propenamide with one or several monomers selected among cationic monomers, monomers comprising at least a strong acid function, partly salified or completely salified, monomers comprising at least a weak acid function, partly salified or completely salified or neutral monomers. The invention also concerns inverse latex or microlatex containing such a polymer. The invention further concerns the uses of said polymer in cosmetic or pharmaceutical compositions, as thickening agents in industrial or household detergents, as additives for assisted recovery of oil, as rheology modifier for drilling fluid or as flocculants for water treatment.

Tris(hydroxymethyl) acrylamidomethane polymer, inverse latex and microlatex containing same, use of said polymer, inverse latex and microlatex

Amphiphilic fluorine derivatives with telomeric structures; preparation procedure and biomedical applications

New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.

Amphiphilic fluorine derivatives with telomeric structures; preparation

Fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.

Amphiphilic fluorine derivatives with telomeric structures

Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.

Amphiphilic compounds derived from amino acids or peptides, their

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Molleges, France

Bernard Pucci