Dr. Willmar Schwabe Gmbh & Co.

Firma Willmar Schwabe

Bernard L Gabard

Shyam Sunder Chatterjee

Hermann E Jaggy

Klaus Klessing

Medicaments containing bilobalid which can be used to control nervous diseases are described.

Pharmaceutical compositions containing bilobalid for the treatment of

The present invention provides corynantheine derivatives of the general formula: ##STR1## wherein R is a hydrogen or alkali metal atom, an ammonium group or the residue of an amine or an alkyl radical containing up to 4 carbon atoms; and the physiologically acceptable acid-addition salts thereof. The present invention also provides processes for the preparation of these corynantheine derivatives and pharmaceutical compositions containing them. Furthermore, the present invention is concerned with the use of dihydrocorynantheine as an antihypertonic.

Corynantheine derivates, processes for their preparation, and their use

Aminodesoxy-1.4;3.6-dianhydrohexitol nitrates of the general formula I, ##STR1## wherein R.sup.1 and R.sup.2 possess the meanings given in claim 1, as well as their pharmacologically acceptable acid-addition salts; processes for the preparation of said compounds, and pharmaceutical compositions containing at least one of said compounds.

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Karlsruhe, Germany

Bernard L Gabard