Immunex Corporation

Virginia Mason Research Center

Benson M Curtis

John Ernest Sims

David J Cosman

Craig A Smith

Linda S Park

Alf D Larsen

James E Scurlock

Mammalian granulocyte-colony stimulating factor (G-CSF) receptor proteins, DNAs and expression vectors encoding mammalian G-CSF receptors, and processes for producing mammalian G-CSF receptors as products of recombinant cell culture, are disclosed.

Granulocyte-colony stimulating factor receptors

DNA sequences encoding granulocyte-colony stimulating factor receptors

A DNA sequence encoding fusion protein is disclosed which comprises GM-CSF and IL-3. Such fusion proteins more biologically active than GM-CSF or IL-3 alone or GM-CSF and IL-3 combined.

DNA sequences encoding fusion proteins comprising GM-CSF and IL-3

A fusion protein is disclosed which comprises GM-CSF and IL-3. Such fusion proteins more biologically active than GM-CSF or IL-3 alone or GM-CSF and IL-3 combined.

Fusion proteins comprising GM-CSF and IL-3

This disclosure describes a method for providing ultra-long local anesthetic effects. The method comprises administering an N,N,N-triethyl-N-alkyl ammonium salt wherein the alkyl group contains from 8 to 16 carbon atoms. The local anesthetic effect producing quaternary ammonium salts and pharmaceutical preparations containing such quaternary salts are also described.

Growing community of inventors

Seattle, WA, United States of America

Benson M Curtis