Alkahest, Inc.

Benson Lu

Viktoria Kheifets

Annette Tennstaedt

Ian Gallager

Marian Castro

Methods and compositions for treating aging-related diseases as well as muscle recovery, prevention of muscle degeneration, and maintenance of muscle are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing disease.

Blood plasma fractions for use in muscle regeneration

Methods and compositions for treating aging-related diseases as well as liver regeneration, prevention of liver degeneration, and maintenance of liver are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing disease.

Blood plasma fractions for use in liver regeneration

Provided herein are methods of inducing liver regeneration in a subject diagnosed with a liver disorder. The method comprises administering a Plasma Protein Fraction (PPF) to the subject. In certain embodiments, the PPF comprises between 83% and 95% albumin in relation to total proteins. The PPF can be produced from plasma obtained from young individuals, for example, humans 40 years of age or younger.

Methods of inducing liver regeneration by administering a plasma protein fraction

Method of treating liver failure with plasma fraction IV-4

The disclosure pertains to methods of improving wound healing. In certain embodiments, the methods comprise administering to a subject a Plasma Protein Fraction (PPF) in an amount that is effective to treat a wound.

Methods of improving wound healing

The disclosure pertains to methods for improving postoperative recovery. In certain embodiments, the methods comprise administering to a subject a Plasma Protein Fraction (PPF) in an amount that is effective to improve or accelerate postoperative recovery.

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San Francisco, CA, United States of America

Benson Lu