Becton Dickinson and Company Limited

Becton Dickinson France

Benoit Fremon

Jean-Bernard Hamel

Tzvetelina Chevolleau

Sébastien Jouffray

Guillaume Lehee

Gaëlle Pouget

Jérémie Vaxelaire

The invention relates to a method for reducing an amount of sub visible particles in a pharmaceutical composition contained in a medical injection device comprising a container () including a barrel () lubricated with a lubricant coating () in contact with the pharmaceutical composition, and a stopper () in sliding engagement within the barrel (), the container comprising a region () extending distally from the distal end () of the barrel which is not accessible to the stopper. During formation of said lubricant coating () on the inner wall of the barrel, the method comprises limiting lubricant from being deposited into said region () extending distally from the distal end () of the barrel.

Method for reducing an amount of subvisible particles in a pharmaceutical composition

Medical stopper

Growing community of inventors

Saint Martin d'Uriage, France

Benoit Fremon