Lucas Meyer Cosmetics Canada Inc.

Maresins Pharma, Inc.

Benoit Cyr

Johane Guay

Brigitte Page

Nathalie Gendron

Brigitte PagÉ

Provided is a plant derived extract including inhibitory activity against one or more extracellular proteases which degrade human tissue matrix. Moreover, the amount of inhibitory activity in an extract can be increased by stressing the plant prior to forming an extract. These extracts are each prepared by a process and demonstrate the ability to inhibit one or more extracellular proteases which degrade human tissue matrix. Libraries of extracts can be prepared from stressed and non-stressed plants, where each of the extracts demonstrate inhibitory activity against on or more extracellular protease inhibitors. Alternatively, semi-purified and purified inhibitory compounds can be isolated from the extracts. In one aspect, these extracts with inhibitory activity can be used during protein purification to minimize degradation due to extracellular proteases.

Inhibitors of extracellular proteases

Described herein is a composition comprising a combination of ginger and goldenrod for the prevention and/or treatment of cold and/or flu infection. Also described is a method of treating or preventing a cold and/or flu infection in a subject in need thereof comprising administering to the subject an effective amount of a composition comprising a combination of ginger and goldenrod.

Growing community of inventors

St. Augustin de Desmaures, Canada

Benoit Cyr