Johns Hopkins University

Gamma Medica-ideas, Inc.

Benjamin M W Tsui

Bradley E Patt

William C Walton

Douglas J Wagenaar

Susan C Harvey

David W Porter

Keith S Peyton

A method for characterizing and locating abnormal tissue in an area of interest in a body is provided. The method may include receiving first and second modality examination data including a plurality of first and second modality examination data segments of the area of interest and determining, by evaluating each first and second modality examination data segment, a set of modality detection candidates based on the first and second modality examination data and a first and second modality feature likelihood model. The method may also include generating a modal or multi-modal correspondence anatomic model of the area of interest by registering the plurality of first and second modality examination data segments, determining one or more modal abnormal tissue detections by fusing the set of modality detection candidates using the modal or multimodal correspondence anatomic model, and providing a modal diagnosis confidence score and a modal anatomic location based on the one or more modal abnormal tissue detections.

Abnormal tissue detection via modal upstream data fusion

Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes.

Multi-aperture single photon emission computed tomography (SPECT) imaging apparatus

Growing community of inventors

Baltimore, MD, United States of America

Benjamin M W Tsui