Studiengesellschaft Kohle Mbh

Benjamin List

Ilija Coric

Luping Liu

Jung Woon Yang

Frank Lay

Martin Nolwenn

Saihu Liao

Sreekumar Vellalath

Lucas Schreyer

Chandra Kanta De

Pilar Garcia Garcia

Xu Cheng

Sonja Mayer

Corinna Reisinger

Wang Xingwang

Roberta Properzi

Sunggi Lee

Philip Stephan Joseph Kaib

Denis Alexandrovich Chusov

Xingwang Wang

Nolwenn Martin

Pilar Garcia-Garcia

Sebastian Armin Schwengers

Yihang Li

Xing Wang Wang

Xu Chen

The present invention relates to chiral phosphoramidimidates, their salts and metal complexes as well as derivatives thereof and their use as catalysts.

Chiral phosphoramidimidates and derivatives thereof

The present invention refers to a process for preparing amines comprising reacting a compound of the formula R&#x2014;CO&#x2014;Rcomprising a carbonyl moiety with a amine compound of the formula HNRRand carbon monoxide in the presence of a catalyst.

Process for preparing amines

The present invention relates to a process for the asymmetric oxidation of nucleophilic organic compounds, particularly metal-free, with peroxide compounds in the presence of a chiral Br&#xf8;nsted acid catalyst. In one detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral imidodiphosphate catalyst. In another detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral phosphoric acid catalyst.

Process for the asymmetric oxidation of organic compounds with peroxides in the presence of a chiral acid catalyst

The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I,  The compounds are suitable as chiral Br&#xf8;nsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.

Chiral imidodiphosphates and derivatives thereof

Chiral disulfonimides having the formula I to III, wherein at least one of the groups A and B in the compound of formula I, C and D of the compound in formula II, and E and F of the compound in formula III is a chiral group, or E and F together form a chiral backbone,

Chiral disulfonimides

A process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives is claimed wherein a biguanid is reacted with acetaldehyde in the presence of an inorganic and/or organic base. The process can be carried out at mild and therefore economical reaction conditions.

Process for preparing 3,6-dihydro-1,3,5-triazine derivatives

A process is claimed for the enantioselective epoxidation of &#x3b1;,&#x3b2;-unsaturated ketones, in which a compound of the general formula I, is reacted with an oxidizing agent to form &#x3b1;,&#x3b2;-epoxy ketones of the general formula II, in which R, R, Rare as defined above. The &#x3b1;,&#x3b2;-epoxy ketones of the general formula II can be obtained in good yields and outstanding enantioselectivities from &#x3b1;,&#x3b2;-unsaturated ketones of the general formula I by epoxidation with hydrogen peroxide in the presence of a chiral catalyst, such as amino compounds and their acid addition salts.

Method for producing chiral &#x3b1;,&#x3b2;-epoxy ketones

The invention relates to a method for producing chiral organic compounds by asymmetric catalysis, using ionic catalysts comprising a chiral catalyst anion. The claimed method is suitable for reactions which are carried out over cationic intermediate stages, such as iminium ions or acyl pyridinium ions. The invention enables the production of chiral compounds with high ee values, that until now could only be obtained by means of costly purification methods.

Organic salts and method for producing chiral organic compounds

A method for the chemoselective hydrogenation of &#x3b1;, &#x3b2; unsaturated carbonyl compounds is disclosed, in which compounds of the formula RRC&#x2550;CR&#x2014;C(O)R, wherein R&#x2014;Rare as defined herein, are reacted with a hybrid donor to form a compound of formula RRCH&#x2014;CH(R)&#x2014;C(O)R, in which R&#x2014;Rare as above. That method permits the selective hydrogenation of &#x3b1;, &#x3b2; unsaturated aldehydes and ketones without the use of metal catalysts.

Method for hydrogenation of &#x3b1;, &#x3b2;-unsaturated carbonyl compounds

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Benjamin List