Hydroglyde Coatings LLC

Boston University

Boston Medical Center Corporation

Benjamin Goldman Cooper

Mark W Grinstaff

Stacy Lee Chin

Ruiqing Xiao

Ducksoo Kim

Karen Buch

The present invention provides polymers which can be used as tissue supplements or lubricants in vivo. The inventive polymers can be used as tissue-interpenetrating hydrogel supplements, viscosupplements, tribosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and injured synovial joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery or malfunction of naturally lubricious mucosal tissue.

Injectable tissue supplement

The invention provides a novel hydrophilic polymer and latex polymer blend coating formulation and compositions thereof, and their use on various devices (e.g., prophylactic and medical devices) to form hydrophilic and flexible coatings with durable lubricity.

Hydrophilic polymer coatings with durable lubricity and compositions and methods thereof

Provided herein are methods comprising the use of a macroinitiator and application protocols to apply a hydrophilic coating to latex, or natural rubber, and compositions resulting from such methods. This coating results in e.g., an increased sense of lubrication when in contact with water or an aqueous solution.

Macroinitiators for hydrophilic coatings on latex and applications thereof

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Lynnfield, MA, United States of America

Benjamin Goldman Cooper