Ethicon, Gmbh

Block Drug Company, Inc.

Benjamin D Fitz

Sasa Andjelic

Christopher M Westergom

Joseph F Zavatsky

Jianguo Jack Zhou

Dwayne Lee Looney

Clifford A Dey

Chetan Anirudh Khatri

Kenneth J Markowitz

Thomas Lee Craven

Michael Justus

Elizabeth Vailhe

Sasa Andjelić

Atul Garg

Ferass Abuzaina

Joseph Zavatsky

Clifford Day

Chetan Anirudh Kharti

The present invention is directed to a resorbable hemostatic nonwoven felt suitable for use in laparoscopic procedures and to methods for manufacturing said felt.

Resorbable laparoscopically deployable hemostat

A bimodal bioabsorbable polymer composition. The composition includes a first amount of a bioabsorbable polymer polymerized so as to have a first molecular weight distribution; a second amount of said bioabsorbable polymer polymerized so as to have a second molecular weight distribution having a weight average molecular weight between about 10,000 to about 50,000 Daltons, the weight average molecular weight ratio of said first molecular weight distribution to said second molecular weight distribution is at least about two to one; wherein a substantially homogeneous blend of said first and second amounts of said bioabsorbable polymer is formed in a ratio of between about 50/50 to about 95/5 weight/weight percent. Also disclosed are a medical device, a method of making a medical device and a method of melt blowing a semi-crystalline polymer blend.

Bioabsorbable polymer compositions exhibiting enhanced crystallization and hydrolysis rates

A novel macromer or mixture thereof is described herein, comprising isocyanatophenyl ether terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the ether group of the isocyanatophenyl ether terminal isocyanate moieties, thereby forming at least two ether linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.

Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant

A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.

Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant

The present invention is directed to a medically acceptable formulation comprising a diisocyanate terminated macromer or mixture thereof, and bio-absorbable desiccant comprising a hygroscopic and/or hydrophilic or combination thereof. The present invention is also directed to methods of use for such formulations for medical procedures.

Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant

A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a diisocyanate macromer is also described herein.

Method of making a diisocyanate terminated macromer

A method for determining the optical retardation and birefringence values of an anisotropic material utilizing a Fourier transform near infrared spectrophotometer operated in at least a portion of the range of wavenumbers between about 4,000 to about 10,000 cm.

Apparatus and method for determining optical retardation and birefringence

The present invention provides dental compositions and methods for treating dentinal hypersensitivity teeth based on the discovery that anionic liposomes possess the capacity to induce mineral formation in the dentinal tubules which partially or fully block them. The subject compositions comprise the liposomes and a suitable carrier and are advantageous in that they can deliver additional agents useful in the treatment of dentinal hypersensitivity, particularly nerve desensitizing agents, to the tubules. The liposomes of the invention are further advantageous in that they are stable to conventional sources of fluoride ion conventionally used as anti-caries agents. The methods of the present invention utilize the subject composition to effect blocking of the dentinal tubules and to simultaneously deliver other treatment agents such as nerve desensitizing agents for the combined benefits thereof.

Growing community of inventors

Brooklyn, NY, United States of America

Benjamin D Fitz