Aktiebolaget Hassle

Bengt A Ablad

Arne E Brandstrom

Stig Ake Carlsson

Enar I Carlsson

Peder Bernhard Berntsson

Gert C Strandlund

Sven E Sjostrand

Lars Ek

Benny Roger Samuelsson

Ortho-para-substituted phenoxy-hydroxypropylamines having the general formula ##STR1## and pharmaceutically acceptable, non-toxic acid addition salts thereof, wherein R.sup.1 is alkyl or hydroxyalkyl, R.sup.2 is alkoxyalkyl or alkylthioalkyl, and R.sup.3 is halogen, alkyl, alkenyl, alkinyl, alkoxymethyl, or alkoxy are disclosed, as are methods for their preparation. Pharmaceutical preparations are prepared whose active ingredients include at least one of the newly discovered phenoxy-hydroxypropylamine compounds. Therapeutically effective doses of these preparations selectively block the .beta.-receptors of the heart making them useful in treating heart diseases in animals including humans.

Phenoxy-hydroxypropylamines, their preparation, and method and

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Goteborg, Sweden

Bengt A Ablad