Evonik Roehm Gmbh

Evonik Operations Gmbh

Evonik Rohm Gmbh

Evonik Degussa Gmbh

Benedikt Hartwig

Norbert Windhab

Peter Niepoth

Juan Tome Alcalde

Steffen Junginger

Hans-Joachim Stiller

Christian Meier

Rosario Lizio

Michael Damm

Andreas Karau

Michael Gottschalk

Andreas Gryczke

Melanie Liefke

Julia Lyubina

Gerhard Geipel

Peter Hölig

Matias Javier Vara Carrera

Maria Del Pilar Ansuategui Panzano

Angela Olf

Maria Del Ansuategui Panzano

María Del Pilar Ansuategui Panzano

Matías Javier Vara Carrera

A body has multiple phases, which have different electron spin resonance spectra that do not result from the simple combination of the ESR spectra of each individual phase.

Masking and subsequently visualising ESR signals using the combination of two materials

The invention relates to a device with a sensor arrangement, which is able to detect magnetic or magnetized oral administration forms after oral take-up, moreover tracks the dissolution thereof via the reduction or disappearance of the magnetic field of the oral administration form, and with a log function, which records a subjective evaluation on the part of the human wearer of the sensor arrangement during or after the oral take-up.

Personalized detection system for detecting magnetic objects in the human organism

The invention refers to a human lactoferrin derived peptide for use as an antigen masking agent in the production of a pharmaceutical composition for delivery of a biological active substance in a mammalian organism, where the biological active substance is able to induce an undesired immune response by the mammalian organism, where the pharmaceutical composition comprises a supramolecular aggregate of the biological active substance and the human lactoferrin derived peptide, with the effect that after delivery of pharmaceutical composition to the mammalian organism, there is no or only a diminished induction of the undesired immune response against the biological active substance.

Human lactoferrin derived peptide for use as an antigen masking agent

The subject matter of the invention is a detector system for detecting magnetic bodies in the human organism, which comprises at least two sensor assemblies, wherein each sensor assembly has one, two or three anisotropic magnetic resistance sensors, of which the axes of weak magnetization point in different directions in pairs, and each sensor assembly has a spacing of 0.5 to 50 cm from the sensor assembly or the other sensor assemblies, and at least two sensor assemblies are tilted at an angle of 0 to 45&#xb0; with respect to one another, and in addition a method for detecting the magnetic flux produced by a magnetic body in the human organism, and the use of the detector system according to the invention for detecting swallowed magnetic bodies and the disintegration of the same in the digestive system.

Detection system for detecting magnetic objects in the human organism

The invention relates to an oral dosage form, comprising at least one biologically active agent, formulation auxiliary substances and magnetizable particles, wherein the dosage form has an at least two phase composition, wherein the phases can dissolve in the body after oral administration due to their formulation and the magnetizable particles are bound in formulation auxiliary substances and are present in a magnetized state, wherein the magnetized particles are present in at least two phases of the dosage form and generate magnetic fields, wherein these phases dissolve at different times in the body after oral administration, and wherein the magnetic field strength with respect to time, position and movement in the body is acquired using a detection system and can be evaluated using a computer-based evaluation system.

Oral dosage form, comprising at least one biologically active agent, formulation auxiliary substances and magnetizable particles

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Darmstadt, Germany

Benedikt Hartwig