University of California

Ben Wu

Kang Ting

B Chia Soo

Wenyuan Shi

Jian He

Fernando Vinuela

Fengxia Qi

Chia Soo

Daniel K Yarbrough

Shunichi Kuroda

Ichiro Yuki

Bruce Rutherford

Kevin Zhang

Larissa V Rodríguez

Arnold Suwarnasarn

Randal Eckert

Sotirios Tetradis

Elizabeth Hagerman

Systems and methods for coating of spiral intracranial aneurysm coils, e.g., a Guglielmi Detachable Coil (GDC), such that only selected surfaces along the spiral coil are coated with a polymer via an atomized polymer deposition process. The resulting device is a detachable aneurysm coil system which preserves the mechanical geometry and flexibility of the coil, and delivers specific agents to promote wound healing.

Systems and methods for fabricating spiral coils with atomized bioactive coatings

Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.

Pharmaceutical compositions for treating or preventing bone conditions

A transcutaneous multimodal delivery device for drug delivery and the methods of making and using the same are provided.

Transcutaneous multimodal delivery system (TMDS)

Recombinant NELL peptides and methods of preparing the same are disclosed.

NELL-1 peptides

The invention generally relates to a bone growth factor, and more particularly to compositions including NELL1, articles of manufacture including NELL1 and methods of using NELL1 to induce bone formation. This invention also provides methods for the expression and purification of NELL1 and NELL2 peptides.

NELL peptide expression systems and bone formation activity of NELL peptide

Provided herein are a composition for promoting cartilage formation or regeneration comprising a NELL gene product and a method of treating cartilage-related conditions using such a composition.

Composition for promoting cartilage formation or repair comprising a NELL gene product and method of treating cartilage-related conditions using such composition

Provided in the present application is a pharmaceutical composition for treating, preventing, or ameliorating a bone or cartilage condition and methods of making and using the same.

NELL-1 peptide

Methods of preparing a NELL peptide are disclosed.

Expression system of NELL peptide

Provided herein is a composition for cartilage formation or regeneration comprising a NELL gene product and a method of treating cartilage-related conditions using such a composition.

Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition

Nell peptide expression systems and bone formation activity of nell peptide

This invention also provides a purified or isolated population of ADSCs that can differentiate into a cell of the leiomyogenic lineage, e.g., smooth muscle or skeletal muscle. In yet another aspect, the population additionally can be differentiated into a lineage selected from the group consisting of osteogenic, adipogenic, chondrogenic, myogenic and neuronal. This invention further provides a composition comprising a substantially homogeneous expanded population of smooth muscle cells. This invention provides a composition comprising a substantially homogeneous expanded population of skeletal muscle cells. Also provided herein is an isolated composition comprising a purified adipose-derived stem cell (ADSC) or progeny of said ADSC and an effective amount of laminin or heparin, effective to induce leiomyogenic differentiation. Diagnositic and therapeutic uses for these compositions are provided herein.

Growing community of inventors

Los Angeles, CA, United States of America

Ben Wu