Smith + Nephew

Wisconsin Alumni Research Foundation

Other

American Cyanamid Company

Acufex Microsurgical, Inc.

Ben Kim Graf

Michael Charles Ferragamo

Bernard Joseph Bourque

William Leo Murphy

Rebecca Ann Blough

Mark D Markel

Paul Alexander Torrie

Raymond A Bojarski

William Richard Davis

Jae Sung Lee

Charles H Brown, Jr

Alfred R Berube

Gary M McCarthy

Joseph H Sklar

Thomas D Rosenberg

Fraser Harvie

Daniel B Ellis

Steve Ek

Yan Lu

Wei Li Fan

Gary Robert McCarthy

Ray Bojarski

Charles Henry Brown, Jr

Rod Berube

Jason LeBeau

Jae-Sam Lee

Geoffrey Baer

Gary R McCarthy

The present invention relates to medical apparatuses and procedures for reconstructing a ligament. There is provided a trephine () comprising an adaptor (), an elongate reamer () coupled thereto, and a reamer support stem (), wherein the reamer support stem is mounted concentrically within the reamer and adaptor, and whereinat least a portion of the reamer support stem is slidably moveable about a longitudinal axis of the trephine.

Trephine

The present disclosure relates to a method of creating a bone tunnel during ligament reconstruction surgery. The method includes placing a guide wire through the femur, the guide wire having a first end portion including a pointed tip and a second end portion; placing a drill mechanism over the first end portion of the guide wire, the drill mechanism having a first end portion including a drill bit and a second end portion including an attachment portion; coupling an adaptor assembly to the attachment portion, the adaptor assembly including a shaft; coupling a drill to the shaft and operating the drill to create a tunnel in the femur; coupling a drill bit assembly to the second end portion of the guide wire and locating the assembly against the drill bit of the attachment portion; and operating the drill to create a counter bore within the tunnel.

Retrodrill system

The present disclosure generally relates to biodegradable and bioresorbable materials having a mineral layer on the surface of the material. More particularly, the disclosure relates to biodegradable and bioresorbable orthopedic devices having a degradable mineral layer on the surface thereof that can be used as a delivery vehicle for biological substances. Also provided are various methods of using the mineralized devices in tissue regeneration, including bone tissue engineering, and methods for producing the mineralized devices.

Biologically active sutures for regenerative medicine

A tissue graft attachment device includes a platform member including a first edge and a second edge connected to the first edge by a top side and a substantially curved bottom side. The platform member defines a slot extending between the first edge and the second edge, a first opening between the slot and the first edge, and a second opening between the slot and the second edge. The tissue graft attachment device includes a first filament passing through the first opening, a second filament passing through the second opening, and a graft connecting element passing through the slot to form a loop.

Attachment device to attach tissue graft

The present disclosure relates to a tissue repair assembly. The assembly includes an interference device and a fixation device coupled to the interference device, wherein the fixation device includes a coupling portion and a capturing portion. Other assemblies and methods are also disclosed.

Tissue repair assembly

The present disclosure relates to a soft tissue graft anchor. The anchor includes a plurality of prongs, each prong including a distal end and a proximal end, wherein the prongs are coupled at their distal ends to form an inner cavity having an opening, at least one of the prongs including a fin, the fin extending perpendicular to a longitudinal axis of the prong and including a pointed end. A tissue graft anchor assembly, a method for tissue repair, and instrumentation for use therewith are also disclosed.

Tissue graft anchor assembly and instrumentation for use therewith

The present disclosure relates to a graft fixation device including a body configured and arranged for passage through a bone tunnel when oriented generally longitudinally with respect to the bone tunnel, and for residing against bone defining an opening to the bone tunnel when oriented generally transversely with respect to the bone tunnel. The body defines an enclosed channel for receiving a member such that the member is substantially evenly distributed about a longitudinal extent of the body so that the body maintains a generally longitudinal orientation during passage through the tunnel, and includes a cross bar about which the member is looped when the body resides against the bone defining the opening to the bone tunnel.

Tissue graft fixation

The present disclosure relates to a fixation device. The fixation device includes a base portion including a first leg, a second leg, and a groove located between the first and second legs and a top portion extending from the base portion. A tissue repair device and a method of tissue repair are also disclosed.

A modular peptide design strategy wherein the modular peptide has two functional units separated by a spacer portion is disclosed. More particularly, the design strategy combines a hydroxyapatite-binding portion and a biomolecule-derived portion. The modular peptides have improved non-covalent binding to the surface of the HA-based materials, and are capable of initiating osteogenesis, angiogenesis, and/or osteogenic differentiation.

Methods of decorating hydroxyapatite biomaterials with modular biologically active molecules

A system for growing tissue based upon layers of an inorganic extracellular matrix, wherein each layer of the inorganic matrix is designed to dissolve at a separate rate and result in sequential growth factor delivery upon its dissolution.

Tissue regeneration system

Growing community of inventors

Madison, WI, United States of America

Ben Kim Graf