Syngenta Crop Protection, Inc.

Syngenta Corporation

Ben Brockbank

Andrew Edmunds

Martin Charles Bowden

David Anthony Jackson

The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim, by reacting a compound of formula (II), with a bromine or chlorine source to form a compound of formula (III), wherein X is chlorine or bromine; reacting that compound with water to form the compound of formula (IV), converting that compound, using a compound of formula (V), wherein Mis the hydrogen cation or an alkali metal ion, alkaline earth metal ion or ammonium ion, into the compound of formula (VI), and treating that compound with a cyanide source in the presence of a base. 

Process for the production of cyclic diketones

The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claimby reacting a compound of formula (II), either with a chlorination or bromination agent or with a compound of formula (III) CI&#x2014;SOR, Rbeing C-Calkyl, C-Chaloalkyl, phenyl or C-Calkyl-substituted phenyl, to form the compound of formula (IV), reacting the compound of formula (IV) with a compound of formula (V) M-O&#x2014;C(O)&#x2014;Y wherein Y is as defined above and Mis the hydrogen cation or an alkali metal ion, alkaline earth metal ion or ammonium ion, to form the compound of formula (VI) and treating that compound with a cyanide source in the presence of a base. 

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Huddersfield, United Kingdom

Ben Brockbank