Baylor College of Medicine

Ben A Oostra

C Thomas Caskey

David L Nelson

Stephen T Warren

Maura Pieretti

Ying-hui Fu

A sequence of the FMR-1 gene is disclosed. This sequence and related probes, cosmids and unique repeats are used to detect X-linked diseases and especially the fragile X syndrome. Also, methods using methylation-sensitive restriction endonuclease and PCR primer probes were used to detect X-linked disease.

Diagnosis of the fragile X syndrome

A sequence of the FMR-1 gene is disclosed. This sequence and related probes, cosmids and unique repeats are used to detect X-linked diseases and especially the fragile X syndrome.

Growing community of inventors

Rotterdam, Netherlands

Ben A Oostra