Covidien LP

Given Imaging Ltd.

Bemina L Rohde

John R Semler

Christopher D Bierl

Kai-Sing J Hwang

Kathleen H Selover

A computerized method of analyzing measurements obtained from the gastrointestinal tract of subject comprising the steps of providing an ingestible capsule () having a sensor () for measuring a parameter of the gastrointestinal tract of a subject, having a subject ingest () the capsule, recording () measurements from the sensor as the capsule passes through the gastrointestinal tract of the subject, transmitting () the measurements to a processor (), conditioning () the measurements to provide data as a function of a time interval, plotting () the data on a display (), providing a query (), on the display, receiving input (or,or,or) from a user in response to the query, setting a marker (-) on the plot () at a location as a function of the input, and determining () a capsule transit time for a selected portion of the gastrointestinal tract as a function of the location of the marker.

System and method of evaluating a subject with an ingestible capsule

A method of determining body exit of an ingestible capsule comprising the steps of providing () an ingestible capsule () having a pressure sensor (), having () a subject ingest the capsule, recording () measurements from the pressure sensor as the capsule passes through at least an end portion of a gastrointestinal tract of the subject, transmitting () the measurements to a processor () outside of the gastrointestinal tract of the subject, identifying () an increasing pressure sequence () in the measurements between a selected start time () and a transmission end time (), comparing () the sequence to a reference (), and using the comparison to make a determination () regarding the capsule exiting the gastrointestinal tract of the subject. The increasing pressure sequence may be the longest increasing pressure sequence in the measurements. The reference may be a logarithmic regression of the measurements. The ingestible capsule may further comprise a temperature sensor () and the method may further comprising the steps of recording () measurements from the temperature sensor as the capsule passes through the end portion of the gastrointestinal tract of the subject, transmitting () the measurements to the processor, analyzing () the temperature measurements for a substantial drop () in the temperature measurements, and using the analysis of the temperature measurements to make the determination regarding the capsule exiting the gastrointestinal tract of the subject.

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Cheektowaga, NY, United States of America

Bemina L Rohde