Richter Gedeon Vegyeszeti Gyar Rt

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Egyt Gyogyszervegyeszeti Gyar

Magyar Tudomanyos Akademia Muszaki Kemiai Kutato Intezete

Bela Stefko

Janos Kreidl

Erik Bogsch

Laszlo Szporny

Csaba Szantay

Bela Kiss

Tibor Keve

Judit M Meszaros Nee Brill

Egon Karpati

Zsolt Szombathelyi

Janos Illes

Maria Farkas Nee Kirjak

Istvan Gebhardt

Jeno Szilbereky

Gabor Megyeri

Ida Deutsch Nee Juhasz

Peter Turcsanyi

Eva Palosi

Ferenc Trischler

Istvan Laszlovszky

Janos Galambos

Dora Groo

Andras Nemes

Lajos Kovacs

Gyorgy Visky

Istvan Hegedus

Andras Vedres

Kalman Burger

Eva Csizer

Denes Mathe

Szilard Vezer

Gyorgy Kalaus

Laszlo Czibula

Erzsebet Lapis

Gabor Blasko

Istvan Racz

Geza Takacsi Nagy

Katalin Nogradi

Jozsef Bakos

Balint Heil

Zsuzsanna Aracs Nee Tischler

Bela Benke

Tamas Mester

Erzsebet Nesmelyi

Anna Kassai Nee Zieger

Laszlo Szotyori

Lajos Szabo

Gyorgy Fekete

Judit Matuz

Katalin Saghy

Katalin Csomor

Tibor Nagy

Aniko Gere

Attila Kis-Tamas

Kalman Szasz

Csaba Lorincz

Janos Fischer

Bela Zsadon

Antal Gimesi

Laszlo Dobay

Janos Sapi

Ferenc Drexler

Maria Zajer Nee Balazs

Maria Gazdag

Lilla Forgacs

Lajos Novak

Csaba Kuthi

Tamas Fodor

Gabor Szepesi

Karoly Zalai

Tibor Blickle

Karoly Pataki

Zoltan Ormos

Maria Stiller

Eva Udvardy Nagy Nee Cserey Pechany

Erzsebet Neszmelyi

Zsuzsanna Aracs Nee Trischler

Jozsef Felmeri

Miklos Toth

Istvan Greiner

Istvan Moldvai

Ida Nee Deutsch

Bela Csukas

Agnes Kelemen

Istvan Jaksa

Gyorgy Thaler

Lajos Szaho

Kalman Graf

Katalin Horvath Nee Berki

Kalmam Gaf

Judit Meszaros Nee Brill, Deceased

Adrien Szuchovszky, Nee Gergely

Arpad Hadhazy

Gyula Csokas

Ivan Rethey, Deceased

Arpadne Kiraly Nee Gyongyver Soos

Erika Bogsch

Viktoria Varkonyi

Erzsabet Neszmelyi

Gaborne Forrai

The invention relates to pharmaceutical compositions against peptic ulcer as well as to a method of treating peptic ulcer. The compositions contain and the method of treatment employs zinc hyaluronate as an active ingredient having a molecular weight in the range of 500,000 to 1,200,000 daltons.

Use of zinc hyaluronate against peptic ulcer

Complexes of deprotonated hyaluronic acid with 3d metal ions of the 4th period of the Periodic Table and compositions containing these complexes as active ingredients or carriers. A process for the preparation of the complexes and compositions (pharmaceutical and cosmetic compositions) containing these complexes as active ingredients are disclosed in which zinc or cobalt (II) hyaluronate is preferably used as active ingredient.

Compositions containing hyaluronic acid associates and a process for preparing same

The invention relates to pharmaceutical compositions of antimicrobial effect as well as a process for the preparation thereof. The pharmaceutical compositions of the invention comprise zinc or cobalt hyaluronate associate (complex) as active ingredient in admixture with a carrier and/or other additives commonly used in the pharmaceutical industry.

Pharmaceutical compositions with antimicrobial activity

Compositions containing cobalt hyaluronic acid complex

Acaricidal compositions and process for preparing same

The present invention relates to racemic or optically active cis octahydro-indolo [2,3-a] quinolizine diester derivatives.

Process for preparing the octahydro-indolo[2,3-a] quinolizine diester

A process for the dehydration of substances, mixtures, primarily condensation reaction mixtures, (e.g. direct esterification, direct acetal formation, direct ketal formation), performed by continuous azeotropic distillation with an organic solvent forming with water an azeotropic mixture of minimal boiling point and unable to mix with water, carried out in such a way that the distillate is cooled at least to the temperature, at which the condensate with the given water content or the organic phase of the condensate is just supersaturated with respect to water, and the organic phase of lower water content obtained in this way is recycled to the distilling boiler. The organic solvents used are e.g. benzene, toluene, 1,2-dichloroethane, chloroform, carbon tetrachloride.

Process for dehydration of condensation reaction mixtures obtained by

New intermediate compounds are disclosed of the formula I, ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl having 1 to 4 carbon atoms, or acid-addition salts thereof of formula Ib, ##STR2## wherein X represents an acid residue, and a process for the preparation of the intermediate compounds.

Racemic and optically active octahydro-indolo(2,3-a) tetrahydropyranyl

An antifungal or anthelmintic method of treatment is disclosed which comprises the step of administering to a mammal in need of said treatment, a pharmaceutically effective amount of a compound of the Formula (I) ##STR1## wherein X is halogen, C.sub.1 to C.sub.6 alkoxy, or a group --NRR.sup.1 in which R and R.sup.1 are each hydrogen or C.sub.1 to C.sub.6 alkyl; and

Aminodiaryl sulfoxide derivatives, process for their preparation and

The invention relates to a new process for preparing 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine of the formula (I), ##STR1## which comprises reacting a pyrimidine derivative of the general formula (II), ##STR2## wherein R.sub.1 stantds for hydrogen or a ##STR3## group, wherein R means a C.sub.1-6 alkyl group or an aryl group optionally substituted by halogen;

Preparation of

The invention relates to a new process for the preparation of nitraminodiaryl sulfoxide derivatives of the formula (I), ##STR1## wherein R and R.sup.1 represent hydrogen or alkyl having from 1 to 6 carbon atoms, and

Nitraminodiaryl sulfoxide derivatives, process for their preparation and

The invention relates to novel 2-halogenated 8- and 1,8-substituted ergolene derivatives of the formula (I) and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I) ##STR1## wherein X stands for a halogen;

2-Halogenated-8- and 1,8-substituted ergolenes

The invention relates to the preparation of cis and trans stereoisomers of racemic and optically active eburnamenine derivatives of the general formula (Ia) ##STR1## or (Ib), ##STR2## wherein R.sub.1 stands for a C.sub.1-4 alkyl group; and

Eburnamenine derivatives, pharmaceutical compositions and methods

The invention relates to a new process for the preparation of aminodiaryl sulfoxide derivatives of the formula (I), ##STR1## wherein X is halogen, alkoxy having from 1 to 6 carbon atoms or a group --(N,R,R.sup.1), in which p1 R and R.sup.1 are hydrogen or alkyl having from 1 to 6 carbon atoms,

Process for the preparation of nitrodiaryl sulfoxides

The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.

Process for the preparation of 2-halogenated ergoline derivatives

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Budapest, Hungary

Bela Stefko