Tarapeutics Science Inc.

Bei Lei Wang

Jing Liu

Li Wang

Ao Li Wang

Wen Chao Wang

Wen Liang Wang

Qingsong Liu

Cheng Chen

Chen Hu

Tao Ren

Xi Li

Shuang Qi

Juan Liu

Feng Ming Zou

Qing Song Liu

Qing Wang Liu

Zi Ping Qi

Jiang Yan Cao

Xiao Fei Liang

Fengchao Lv

Xi Xiang Li

Provided is a novel PDGFR kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. Further provided are use and a method of the compound of formula (I) for preventing or treating conditions associated with PDGFR kinase activity, particularly use and a method for preventing or treating conditions associated with PDGFRα and/or PDGFRβ kinase activity.

Pyrazole derivatives and use thereof

An inhibitor of a wild type and Y641F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity. 

EZH2 inhibitor and use thereof

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Anhui, China

Bei Lei Wang