Alfasigma S.p.a.

Mendes S.r.l.

Alfa Wassermann, Inc.

Beatrice Vitali

Giuseppe Claudio Viscomi

Paola Maffei

Seok-Jin Kim

Vittoria Lauro

Fiorella Calanni

Federica Cruciani

Barbara Luppi

Angela Abruzzo

The present invention relates to medical devices in the form of mucoadhesive films for the release of live lactic bacteria and bifidobacteria (probiotics) and/or for the release and maintenance of their pharmacologically useful enzyme activities.

Mucoadhesive devices for the release of probiotics and for the maintenance of their enzyme activities

The invention relates generally to pharmaceutical compositions comprising rifaximin effective at treating vaginal infections, and in particular bacterial vaginosis. The pharmaceutical compositions comprising rifaximin granules are characterized in that they release rifaximin in the vagina in a controlled way. The present invention also relates to processes for preparation of the rifaximin pharmaceutical compositions and their use in the treatment of vaginal infections. Effective dosages and courses of treatment useful and effective at recovering from the disease and preventing any possible relapse are also provided.

Pharmaceutical compositions comprising rifaximin, processes for their preparation and their use in the treatment of vaginal infections

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Bologna, Italy

Beatrice Vitali