Owens-illinois, Inc.

Technicon Instruments Corporation

Anatrace Inc.

Owens-illionis, Inc.

Barry Watson

Philip J Breno

Paul R Maguire

Wayne J Zitkus

Robert J Aul

Frank E Semersky

Don N Gray

Anthony P Schmid

Mary B Douglas

Christopher S Youngen

Robert D Cichy

A biocompatable multi-layer article suitable for use in blood oxygenation is disclosed. The article is made up of a microporous polypropylene tube, a perm-selective, water vapor impermeable, carbon dioxide and oxygen permeable, homogeneous layer directly adhered to the polypropylene tube and active heparin linked through a covalent bond to the permselective layer. The polypropylene tube has an inside diameter from 240 to 400 .mu.m, a wall thickness from 10 to 50 .mu.m, and a porosity from 20 to 80 percent. The perm-selective layer is a polysulfone which has the structure ##STR1## where R is an alkyl group having 16 carbon atoms and n is 3,500 to 35,000. A method for producing a biocompatible multi-layer article suitable for use in blood oxygenation is also disclosed. The method involves the steps of immersing a microporous polypropylene tube which has an inside diameter from 240 to 400 .mu.m, a wall thickness from 10 to 50 .mu.m, and a porosity from 20 to 80 percent in a solution of a polysulfone which has the foregoing structure, and heating the coated polypropylene tube to a temperature that is above the softening point but below the decomposition temperature of the sulfone, e.g., in an oven heated to 70.degree.-150.degree. C. A new poly(sulfone-alpha-olefin) is also disclosed. The new poly olefin has the structure of Formula 2, below: ##STR2## where the R' groups can be the same or different, most of them are C6 to C16 alkyls, n is an integer of at least 6, preferably from 3,500 to 35,000, and some of the repeating groups have the structure of Formula 3, below: ##STR3## where R' is a bromoalkyl group having from 1 to 26 carbons, a methyl or ethyl ester of an alkyl carboxylic acid having from 1 to 26 carbons, or an alkyl aldehyde having from 1 to 26 carbons.

Poly(sulfone-alpha-olefin) composite permselective membrane article for

Asymmetrical layered structures such as asymmetrical films are disclosed. The main body section contains a multitude of pores (voids). A thin surface skin is free of pores. The entire structure is fabricated from a polyalkylene sulfone resin in which the alkylene moiety contains 6 to 18 carbon atoms. Processes for preparing the structures also are disclosed. The structures are semi-permeable to gases and are used as membranes to enrich the oxygen content of oxygen/nitrogen mixtures.

Method of making asymmetrical layered structures from polyalkylene

Asymmetrical layered structures of polyalkylene sulfone resins

An electrochemical system using a flow-through electrode design employing a dual separation method to lower electrode poisoning due to large chemical species and interference current due to small electroactive species is disclosed. The system includes a fluid inlet to a reaction chamber and a fluid outlet from the chamber, with the chamber in contact with an electrode system. The electrode is protected from poisoning and interference by a membrane system comprising a semipermeable membrane having well defined pore ranges therethrough which allow diffusion of only selected size small molecules. A unique sample stream flow control coupled with the size selective membrane combine to remove large, or macromolecule poisoning species and substantially reduce small species interference at the active surfaces of the electrode means.

Flow-through electrochemical system analytical method

Urea nitrogen analyzer

Glucose analyzer

This invention relates to a glass electrode structure. More specifically, the present invention relates to a glass electrode having a curved sensor tip for use in determining gas in an electrochemical membrane diffusion cell.

Glass electrode for membrane diffusion analysis of gases

An inline magnetic mixer for flowing fluids. A magnetic particle is contained within a flow tube through which a fluid passes. A coil made of electrically conductive material is positioned in close proximity to the flow tube and outside the flow tube. A low voltage, oscillating electrical supply energizes the coil. This sets up an oscillating magnetic field within the flow tube which causes the magnetic particle to oscillate longitudinally within the flow tube, thereby mixing the fluid stream passing through the flow tube.

Magnetic mixer

Growing community of inventors

Toledo, OH, United States of America

Barry Watson