Sherwood Medical Company

Johnson & Johnson Products, Inc.

Johnson & Johnson Patient Care, Inc.

Bonewax, LLC

Barry E Constantine

Laura Lee Bolton

Scott M Britton

Gloria Y Lott

Teresa H Haddock

The present invention provides methods and compositions involving resorbable hemostatic agents that have the essential absence of microfibrillar collagen. Resorbable hemostatic agents of the present invention comprise polyethylene glycol, which controls bleeding in tissue and does not delay or interfere with healing. The resorbable hemostatic agents of the present invention are biodegradable and biocompatible agents that effectively control bleeding in bone and other tissue without interfering with the subsequent healing of the tissue.

Hemostatic compositions and methods

A wound dressing comprises a vapor permeable plastic film coated on one side with an adhesive about the periphery of a wound contacting window in the central portion of the dressing. A pair of release liners covers the adhesive coating and include tabs so that the release liners can be peeled from the adhesive coating. Strips are provided adjacent to and at opposite lateral sides of the wound contacting window to change abruptly the resistance to peeling of the release liners from the adhesive coated film. Accordingly, when the user feels this change in resistance, he or she knows that the wound contacting window and a small portion of the adhesive about the periphery thereof is uncovered which allows the dressing to be anchored about the patient's wound with the release liners partially in place and the wound contacting window exposed. This minimizes the tendency of the film to wrinkle and/or to fold on itself such that the adhesive adheres to itself.

Wound dressing having peeling-force varying release liners

A wound dressing comprises a vapor permeable plastic film coated on one side with an adhesive about the periphery of a wound contacting window in the central portion of the dressing. A pair of release liners covers the adhesive coating and include tabs so that the release liners can be peeled from the adhesive coating. Means are provided adjacent to and at opposite lateral sides of the wound contacting window to change abruptly the resistance to peeling of the release liners from the adhesive coated film. Accordingly, when the user feels this change in resistance, he or she knows that the wound contacting window and a small portion of the adhesive about the periphery thereof is uncovered which allows the dressing to be anchored about the patient's wound with the release liners partially in place and the wound contacting window exposed. This minimizes the tendency of the film to wrinkle and/or to fold on itself such that the adhesive adheres to itself.

Wound dressing

An absorbent adhesive dressing is disclosed which is intended for use in treating wounds of the ulcer and burn type where there is significant wound exudate, which has a three layer sandwich-type construction having an occlusive film (e.g. polyethylene, polypropylene etc.) as the outer layer, an absorbent layer of fibers (e.g. cellulose, synthetic fibers etc.) as the middle layer, and a wet-stick adhesive as the inner wound facing adhesive layer, wherein said adhesive layer is a continuous, substantially non-pourous layer having a porosity of less than 0.4 cc/sec/in.sup.2 which is made from an acrylic polymer having both hydrophilic and hydrophobic characteristics (e.g. a wet-stick adhesive polymer formed from emulsion polymerization in water of N-vinyl caprolactam with n-butyl acrylate or with 2-ethylhexyl acrylate, or both, and which because of the hydrophilic nature of the polymer allows exudate to pass through the adhesive layer to the absorbent fibers of its middle layer without degrading the adhesive or its performance, and where the peripheral outer edges of the layers are optionally sealed.

Absorbent adhesive dressing

Debriding tapes are disclosed which contain a proteolytic enzyme useful for debridement of eschar and necrotic tissue, e.g., subtilisin, bromelain, in dry powdered form on the adhesive mass surface of an occlusive or semi-occlusive surgical adhesive tape.

Growing community of inventors

Island Heights, NJ, United States of America

Barry E Constantine