Mayo Foundation for Medical Education and Research

Barry A Borlaug

Samuel J Asirvatham

Vojtech Melenovsky

Christopher V DeSimone

Prakriti Gaba

This document relates to devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure.

Pericardial modification systems and methods for heart failure treatment

This document relates to devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. The methods for treating diastolic heart failure of a patient include: creating an opening in a parietal layer, and only in the parietal layer, of a pericardial tissue of the patient. The creation of this opening reduces pressure exerted by the pericardial tissue on a heart of the patient.

Pericardial modification devices and methods can be used for the treatment of heart conditions. For example, this document describes devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. In one example embodiment, a method for treating diastolic heart failure includes creating an opening in a patient's pericardial tissue, or removing a portion of the patient's pericardial tissue. The creation of the opening or the removing of the pericardial tissue reduces pressure exerted by the pericardial tissue on the patient's heart. The pericardial modification procedures are performed while avoiding trauma to the epicardial surface of heart as well as the phrenic nerves.

Devices and methods are described for the treatment of heart conditions such as heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. Intraoperative test procedures for assessing the efficacy of the pericardial modification procedure are also described.

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Rochester, MN, United States of America

Barry A Borlaug