Abbott Laboratories Corporation

Barbara S Arnholt

Terrence B Mazer

Joseph E Walton

Ronita K Geckle

John J Kropczynski, Jr

Sherri A Walker

Frank A Murawski

Rhonda Cole Walsh

Daniel Hamilton

Michael V Walsh

Monty L Evans

Larry G Tucker

Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.

Sustained release dosage form unit having latex coating and method of making the same

Growing community of inventors

Worthington, OH, United States of America

Barbara S Arnholt