Motorola Corporation

The Boeing Company

Lucent Technologies Inc.

Clinical Micro Sensors, Inc.

Barbara M Foley

Huinan J Yu

Davis H Hartman

Earnest J Johnson

Christopher K Chun

Fred V Richard

Sean Gallagher

Chan-Long Shieh

Wenbin Jiang

Cary D Perttunen

Karen E Jachimowicz

Daniel B Schwartz

William M Peterson

Diana C Chen

Vi-En Choong

George Edward Charles

Gary W Grube

Muhammed Afzal Shahid

George N Maracas

James H Knapp

Shun-Meen Kuo

Kurt W Eisenbeiser

Rong-Fong Huang

Piotr Grodzinski

Xunhu Dai

Fred S Hickernell

Peter F Lilienthal, Ii

Jeremy W Burdon

Jeffrey M Finder

Danny L Thompson

Mark W Beranek

Cynthia G Briscoe

David Galloway

David Wilcox

Robert Marrero

Yuk-Tong Chan

Nicholas J Naclerio

Jaymie Robin Sawyer

Douglas P Fayden

Cynthia Ann Gorsuch Briscoe

Natalia Briones

The invention relates to a microfluidic device with microchannels that have separated regions which have a member of a specific binding pair member such as DNA or RNA bound to porous polymer, beads or structures fabricated into the microchannel. The microchannels of the invention are fabricated from plastic and are operatively associated with a fluid propelling component and detector.

Biochannel assay for hybridization with biomaterial

A teleconference system including a plurality of personal presence cells positioned at a local communication site and at a remote communication site. The plurality of personal presence cells are characterized as either sensor cells or display cells. The sensor cells include at least one video camera positioned to sense and transmit an image of the local participant, and an image screen positioned to reflect an image of the local participant toward the at least one video camera and for viewing of an image through the screen. The display cells each include at least one projection display positioned to display a multi-dimensional image of a remote participant on a display screen. A transmission link interfaces the plurality of personal presence cells positioned at the local communication site and the plurality of presence cells positioned at the remote communication site.

Teleconference system with personal presence cells

High quality epitaxial layers of compound semiconductor materials can be grown overlying large silicon wafers by first growing an accommodating buffer layer on a silicon wafer. The accommodating buffer layer is a layer of monocrystalline oxide spaced apart from the silicon wafer by an amorphous interface layer of silicon oxide. The amorphous interface layer dissipates strain and permits the growth of a high quality monocrystalline oxide accommodating buffer layer. The accommodating buffer layer is lattice matched to both the underlying silicon wafer and the overlying monocrystalline compound semiconductor layer. Any lattice mismatch between the accommodating buffer layer and the underlying silicon substrate is taken care of by the amorphous interface layer. To further relieve strain in the accommodating buffer layer, at least a portion of the accommodating buffer layer is exposed to a laser anneal process to cause the accommodating buffer layer to become amorphous, providing a true compliant substrate for subsequent layer growth.

Semiconductor structure including a partially annealed layer and method of forming the same

A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that transmits excitation radiation from a source port into each one of the electrophoresis channels. The optical waveguide system is defined by regions, within either the cover or substrate, that have an index of refraction higher than that of the surrounding material.

Capillary electrophoresis devices incorporating optical waveguides

A multilayered microfluidic device having a substantially monolithic structure is formed by sintering together a plurality of green-sheet layers. The substantially monolithic structure has an inlet port for receiving fluid, an outlet port for releasing fluid, and an interconnection between the inlet port and the outlet port. The substantially monolithic structure may also include a variety of components to enable useful interaction with the fluid, such as electrically conductive pathways, heaters, fluid sensors, fluid motion transducers, and optically transmissive portions. The components are preferably fabricated using thick-film or green-sheet technology and are preferably co-fired with and sintered to the green-sheet layers to become integral with the substantially monolithic structure.

Integrated multilayered microfludic devices and methods for making the same

An apparatus for measuring at least one selected physical condition of an animate subject is disclosed. The apparatus comprises: (a) a light source; (b) a light receiver that receives resultant light from the light source via the subject; and (c) an information processor connected with the light receiver. The processor receives indication of the resultant light from the light receiver and evaluates the indication to effect the measuring. The processor is implemented in a unitary structure with the light source and light detector that is borne upon a single silicon substrate. The apparatus may further comprise a first interface element coupled with the processor to facilitate communication with the light receiver, and a second interface element coupled with the processor that includes communication means for conveying messages to remote loci. The first and second interface elements are implemented in the unitary structure. The method of the present invention comprises the steps of: (a) providing an apparatus implemented in a unitary structure borne upon a single silicon substrate; and (b) evaluating the indication provided by the apparatus to effect the measuring. The unitary structure is comprised of a monolithic structure having a first portion implemented in silicon, and having a second portion implemented in at least one compound semiconductor material.

Apparatus and method for measuring selected physical condition of an animate subject

A bio-molecule analyzer includes an array of addressable light sources, a photoconductive layer of material having a layer of electrically conductive material on a surface thereof mounted on the array of addressable light sources, and a plurality of test sites on an opposing surface of the photoconductive layer of material defined by the plurality of light sources. A solution containing a plurality of bio-molecules is positioned in electrical contact with the plurality of test sites. An electrical potential is connected between the solution and the layer of electrically conductive material, whereby the array of addressable light sources emit beams of light through a plurality of portions of the photoconductive layer of material to define the test sites and complete electrical circuits between the layer of electrically conductive material and the solution.

Bio-molecule analyzer with photosensitive material and fabrication

A method of bonding bio-molecules to a test site including providing a substrate having a test site defined on a surface thereof, providing a solution containing a plurality of probe molecules and bonding material, directing light from a light source onto the test site so as to cause the bonding material to bond the probe molecules to the test site.

Method of bonding bio-molecules to a test site

A method of fabricating one or more arrays of bio-molecule test sites including providing a solution containing bio-molecule probes in contact with the surface of a substrate, using orthogonal acoustic waves to concentrate the bio-molecule probes at a node intersection, bonding the bio-molecule probes on the substrate at the node intersection to form a test site, and removing the solution leaving the bio-molecule probes attached to the surface at the test site. The steps are repeated as often as desired, using different bio-molecule probes, to produce one or more arrays of test sites.

Method of fabricating bio-chip arrays

A projection system for a computer has an electronic slide (94) that is coupled to an electronic image signal (84) from a processor (82) in the computer (50). Projection optics (102) focus an optical image from the electronic slide (94) onto a screen (58).

Projection system for a computer

A bio-molecule analyzer including a plurality of test sites on a transparent substrate, each test site having probe molecules attached thereto. An array of addressable light sources are positioned in optical alignment with a corresponding test site. A solution containing sample molecules is positioned in contact with the plurality of test sites. A detector array having a plurality of photodetectors positioned in optical alignment with the array of addressable light sources, one photodetector corresponding to each light source, and a light filter positioned between the detector array and the plurality of test sites for absorbing the light from the light sources and transmitting the light from the test sites to the detector array.

Bio-molecule analyzer with detector array and filter device

An optical hinge (20) provides one or more free space optical communication links through the hinge (17) of an instrument (10). The optical links include a transmitter (24) in one section (14) of the instrument (10) and a receiver (34) in the other section (16) of the instrument (10). An optical coupler (27) connects the transmitter (24) to the receiver (34) through a hinge (17).

Optical hinge

An optoelectronic module is disclosed in which an optoelectronic device is precisely aligned with an optical fiber. The optoelectronic module comprises a first member, a second member for supporting an end of the optical fiber in a fixed position relative the first member along an axis, and a third member for mounting at least one optoelectronic device. A plurality of positioning members are adjustably positioned on the first member for supporting the third member to maintain aligned relation of the optoelectronic device with the axis.

Precision alignment of optoelectronic devices

Growing community of inventors

Phoenix, AZ, United States of America

Barbara M Foley