Pierce Biotechnology, Inc.

Life Technologies Corporation

Barbara J Kaboord

Kay K Opperman

Christopher Laurence Etienne

Jean-Samuel Schultz

Scott D Meier

Joanna Geddes

Sandro David Klein

Greg Hermanson

Greg Nagy

Christopher Wojewodzki

Aaron McBride

Formulations for extraction and stabilization of G-Protein Coupled Receptors (GPCRs), kits and methods for their use for extracting GPCRs from biological specimens (e.g., cells and tissues), and methods for making such formulations in bulk scale are described. GPCRs extracted from cells and tissues using the described formulations remain in a functional, solubilized form over extended time periods.

G- protein coupled receptor extraction formulations

Dialysis devices include a frame defined by a plurality of sidewalls that are impermeable to a sample being dialyzed, a pair of dialysis membranes that are each associated with an opposing face of the plurality of sidewalls such that the plurality of sidewalls and the pair of dialysis membranes define a sample chamber, an outer shell surrounding at least a portion of the pair of dialysis membranes, and a cap selectively associated with the sample chamber. The cap can be selectively associated with the sample chamber via an attachment mechanism that is configured to provide aural and/or haptic feedback when the cap forms a tight association with the sample chamber. The cap can be a sensor cap having one or more probes for measuring at least one property of fluid inside and/or outside the sample chamber and a transmitter for transmitting data captured at the probe(s) to a destination device.

Dialysis devices and sensor caps and systems and methods incorporating the same

Modified nucleotides, and methods to modify nucleotides with a moiety or label, such as biotin, that permits their detection and results in a modified nucleotide, and methods of use of the modified nucleotide in quantitative and qualitative assays.

Modified nucleotides methods and kits

Modified nucleotides

Growing community of inventors

Oregon, WI, United States of America

Barbara J Kaboord