Sigma-tau Industrie Farmaceutiche Riunite S.p.a.

Humanitas Mirasole S.p.a.

Barbara Bottazzi

Alberto Mantovani

Marco Presta

Marco Rusnati

Martino Introna

Antonio Inforzato

Annunciata Vecchi

Ilaria Laface

Tamara Gulic

The present invention refers to an antibody able to recognize and bind to an epitope comprised in a sequence of human Migration Stimulating Factor (MSF), and that doesn't recognize and bind human Fibronectin 1 (hFn1) and to uses in diagnostic methods and therapy.

Anti-human migration stimulating factor (MSF) and uses thereof

Pharmaceutical compositions are described containing a long pentraxin PTX3, particularly human PTX3, for the therapy of infectious and inflammatory or tumor diseases; expression vectors containing cDNA coding for PTX3; recombinant host cells transfected with such vectors; a method for producing substantial amounts of PTX3 involving the culturing of such cells, and the use of said vectors in the gene therapy of tumors.

Pharmaceutical compositions containing the long pentraxin PTX3

The use of the long pentraxin PTX3 (PTX3) or one of its functional derivatives is described for the preparation of medicament which inhibits the biological activity of the growth factor FGF-2, useful for the prevention and treatment of diseases brought about by an altered activation of said growth factor FGF-2.

Use of the long pentraxin PTX3 for the treatment of diseases caused by an altered activation of the growth factor FGF-2

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Milan, Italy

Barbara Bottazzi