The Procter Gamble Company

Other

The Proctor 'Gamble Company

Barbara A Kozikowski

Charles Raymond Degenhardt

The present invention relates to compositions and methods for inhibiting plaque. In particular, this invention relates to oral compositions comprising: (a) a safe and effective amount of a carboxy-substituted polymer active agent having the formula ##STR1## or the salts thereof, wherein R is a C.sub.1 -C.sub.8 alkyl group, n is in the range of from 0 to about 2,000, m is in the range of from about 10 to about 2,000, and p is in the range of from about 1 to about 10; and (b) a pharmaceutically acceptable carrier. These compositions inhibit plaque without staining the tooth surfaces which are contacted with the composition. This invention also relates to a method of inhibiting plaque on tooth surfaces in the oral cavity. This method involves applying a safe and effective amount of the carboxy-substituted polymer active agent to the oral cavity. Such an application is typically made by applying the above-described oral compositions containing the carboxy-substituted polymer to the tooth surface. The application does not stain the teeth on which it is made.

Use of a carboxy-substituted polymer to inhibit plaque formation without

The present invention relates to compositions and methods for inhibiting plaque. In particular, this invention relates to oral compositions comprising: (a) a safe and effective amount of a carboxy-containing copolymer having the formula ##STR1## or the salts thereof, wherein n is in the range of from about 200 to about 14,000, m is in the range of from about 2 to about 5,000, and p is in the range of from 1 to 3; and (b) a pharmaceutically acceptable carrier. These compositions inhibit plaque without staining the teeth which are contacted with the composition. This invention also relates to a method of inhibiting plaque on tooth surfaces in the oral cavity. This method involves applying a safe and effective amount of the carboxy-containing copolymer active agent to the oral cavity. Such an application is typically made by applying the above-described oral compositions containing the carboxy-containing copolymer to the oral cavity. The application does not stain the teeth on which it is made.

Use of a carboxy-containing copolymer to inhibit plaque formation

The present invention relates to compositions and methods for inhibiting plaque. In particular, this invention relates to oral compositions comprising: (a) a safe and effective amount of a plaque-inhibiting carboxy starch polymer comprising the formula ##STR1## wherein W and X are independently selected from CH.sub.2 OH, CHO and CO.sub.2 H, or the neutralized carboxylic acid salts thereof, Y and Z are independently selected from CHO and CO.sub.2 H, or the neutralized carboxylic acid salts thereof, n is in the range of from about 5 to about 2500, m is in the range of from 0 to about 2500, provided that the sum of n and m ranges from about 5 to about 2500, and the degree of carboxylation of said active agent ranges from about 1 to about 3; and (b) a pharmaceutically acceptable carrier. These compositions inhibit plaque without staining the teeth which are contacted with the composition. This invention also relates to a method of inhibiting plaque on tooth surfaces in the oral cavity. This method involves applying a safe and effective amount of the carboxy starch polymer active agent to the oral cavity. Such an application is typically made by applying the above-described oral compositions containing the carboxy starch polymer to the oral cavity. The application does not stain the teeth on which it is made.

Use of a carboxy starch polymer to inhibit plaque without tooth staining

Anticalculus and antiplaque oral care compositions containing geminal diphosphonate polymer anticalculus agents and a pharmaceutically acceptable carrier, and method for inhibiting formation of calculus and plaque in the oral cavity by treatment with geminal diphosphonate polymers.

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Cincinnati, OH, United States of America

Barbara A Kozikowski