Roquette Freres

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Dsm IP Assets B.v.

Roquett Freres

Baptiste Boit

Philippe Lefevre

Pierrick Duflot

Damien Passe

José Lis

Pierre Lanos

Geoffrey Lacroix

Fabrice Buquet

Mathias Ibert

Alain Francois

Laurent Rossi

Veronique Rebuffel

Aline Lecocq

Heike Jerosch

Jean-Michel Roturier

Gregory Le Bihan

Maarten Job Van De Graaf

Véronique Rebuffel

Sébastien Vesin

Jean-Charles Baritaux

Guillaume Fiey

Oumar Toure

Antoine Salome

Emeric Bergmann

Matthieu Ramette

Claude-Gilles Dussap

Frédérick Dehay

Dominique Ortiz De Zarate

Frederick Dehay

Jose Lis

A directly compressible composition includes more than 30% by weight of allulose. The directly compressible composition can form tablets. A method for the manufacture of allulose granules includes: a step (a) of preparing a granulation liquid comprising allulose; a step (b) of granulating powdery allulose, by applying the granulation liquid obtained in step (a) onto moving powdery allulose; a step (c), simultaneous with step (b), of drying the granules obtained in step (b); a step (c′) of maturation of the granules obtained in step (c); and a step (d) of recovering the granules obtained in step (c) or (c′).

Sugar compositions for tableting by direct compression

A new method for producing D-allulose crystals that allows for a continuous production process and ensures a high yield. Also, new D-allulose crystals. Further, the use of a nanofiltration unit in a method for producing D-allulose crystals to improve the yield and/or quality of the resulting crystals.

Method for producing D-allulose crystals

A D-allulose syrup including, besides D-allulose, a D-allulose dimer mass content, expressed in terms of dry mass, lower than 1.5%. Also, a method for producing the syrup and to the use thereof for producing food or pharmaceutical products.

Crystallisable d-allulose syrups

A D-allulose syrup including, besides D-allulose, a D-allulose dimer mass content, expressed in terms of dry mass, greater than 1.5%. Also, a method for producing the syrup and the use thereof for producing food or pharmaceutical products.

Non-crystallisable D-allulose syrups

A process for preparing a coagglomerate of crystalline mannitol and of starch includes spray-drying or granulating a mixture of a 'solution' of mannitol and of starch, the starch being suspended in the mannitol solution. The coagglomerate has a laser volume mean diameter D4,3 between 60 and 500 &#x3bc;m, and a mannitol/starch ratio is between 99.5/0.5 and 50/50. The coagglomerate, when mixed with 1.2% of magnesium stearate and formed into a cylindrical tablet with convex faces, a diameter of 13 mm, a thickness of 6 mm, and a weight of 0.734 g, has a crushing strength greater than 120 N. 100 g of said coagglomerate has a flow of between 3 and 15 seconds, measured according to European Pharmacopoeia 5.0, volume 1, 01/2005: 20916, section 2.9.1.6.

Compressible and free-flow co-agglomerates of mannitol and granual starch

A directly compressible composition includes more than 30% by weight of allulose. The directly compressible composition can form tablets. A method for the manufacture of allulose granules includes: a step (a) of preparing a granulation liquid comprising allulose; a step (b) of granulating powdery allulose, by applying the granulation liquid obtained in step (a) onto moving powdery allulose; a step (c), simultaneous with step (b), of drying the granules obtained in step (b); a step (c') of maturation of the granules obtained in step (c); and a step (d) of recovering the granules obtained in step (c) or (c&#x2032;).

A method for determining the degree of polymerization of a polymer is disclosed, the polymer being contained in a sample (), the method comprising the following steps:

Method for determining a degree of polymerisation of a polymer

The invention relates to a hydrogenated glucose polymer composition having a total fibre content of more than 50% as determined by the AOAC 2001.03 method, and a dry weight reducing sugar content, SR, lower than 800 ppm. The invention also relates to a method for producing said composition. The invention is also directed to a food or pharmaceutical product comprising said composition.

Hydrogenated glucose polymer composition containing dietary fibres

The present invention relates to mannitol granules that are of use for the preparation of tablets by direct compression, which do not require a small amount of lubricant in order to be processed. The present invention also relates to a process for preparing such granules. The present invention also encompasses pulverulent compositions comprising these granules, and also direct compression processes using these pulverulent compositions. Finally, the present invention relates to tablets composed of these pulverulent compositions.

Mannitol granules for direct compression

The present invention relates to maltooligosaccharides, the content of &#x3b1;-1,4-glycosidic bonds of which is between 70% and 80% of the total number of 1,4-type glycosidic bonds. The invention also relates to the method for manufacturing these maltooligosaccharides. Said maltooligosaccharides afford all the benefits of fiber-based foods, with an extremely low nutritional value. Such a compromise is particularly advantageous for use in healthy balanced diets, but also in the treatment and/or prevention of the pathology of diabetes. The invention also relates to the use of said maltooligosaccharides in the fields of human food and animal feed.

Fiber-rich maltooligosaccharides having low glucose bioavailability, method of manufacture thereof and use thereof in human food and animal feed

A process for manufacturing succinic acid as obtained by fermentation is provided including crystallizing the succinic acid from an aqueous solution, separating the crystals from the mother liquor, treating the mother liquor by nanofiltration and recycling the treated mother liquor to the crystallization step. This process exhibits a high yield in terms of succinic acid crystals recovery and allowing to achieve a final product with a low content of saccharides.

Process for manufacturing succinic acid from a fermentation broth using nano filtration to purify recycled mother liquor

Coagglomerates of mannitol, whose laser volume-average diameter D4,3 is between 1 and 200 &#x3bc;m, and of granular starch, are characterized in that they have a disintegration behavior determined according to a test A such that the relaxation time measured is between 30 and 100 seconds and the swelling force is between 0.8 and 3.0 N.

Orodispersible mannitol

Co-agglomerates of crystalline mannitol and granular starch, characterized in that they have a compressibility, as determined according to a test A, higher than 120 N, and preferably of 200 to 450 N, and a flow time, as determined according to a test B, of 3 to 15 seconds, and preferably of 4 to 8 seconds.

Compressible and free-flow co-agglomerates of mannitol and granular starch

A process for producing a composition which is particularly rich in D-mannitol, the latter being present in the form of crystals having a volume average diameter greater than 20 pm, wherein the crystals correspond to a very large extent to the &#x3b4; polymorph. This process makes use of the evaporative crystallization technique, in which the seeding and then the controlled growth of the crystals is carried out at different evaporation rates. Finally, very pure &#x3b4; crystals are advantageously obtained, which have a better compressibility than the &#x3b1; and &#x3b2; homologues thereof and which, by virtue of the sizes thereof, result in a powder which is not subject to caking.

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Lestrem, France

Baptiste Boit