Genomatica, Inc.

Other

Industrial Microbes, Inc.

Dow Agrosciences LLC

Reg Life Sciences, LLC

Ffa Sciences LLC

Pioneer Hi-Bred International, Inc.

Alan Marc Kleinfeld

Kleinfeld, Alan M.

Baolong Zhu

James Patrick Kampf

Thomas Kwan

Andrew Henry Huber

Andreas W Schirmer

Zhihao Hu

Stephanie Rhianon Jones

Emanuela E Popova

Elizabeth Jane Clarke

Derek Lorin Greenfield

Noah Charles Helman

Eli S Groban

Vikranth Arlagadda

Elizabeth J Clarke

Derek L Greenfield

Cindy Chang

Sungwon Lee

Xuezhi Li

Donald J Merlo

Scott Bevan

Scott B Bintrim

Timothy Denver Hey

Thomas Meade

Stephen B Del Cardayre

Louis G Hom

Haibo Wang

Patricia C Apel-Birkhold

Weiting W Ni

Amanda D Schleper

Ze Sheng Li

Cory M Larsen

Jon Christopher Mitchell

Jarred Kenneth Oral

Jun-zhi Wei

William T Beeson

Samatha L Griffin

Navdeep Mutti

Jon C Michell

Elizabeth Clarke

Methods and compositions for the oxidation of short alkanes by engineered microorganisms expressing enzymes are described, along with methods of use.

Heterologous expression of short-chain monooxygenases in microorganisms

Improved soluble methane monooxygenases and soluble methane monooxygenase systems are provided.

Methane monooxygenase enzymes

The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells. The disclosure further relates to microorganisms for expressing the omega-hydroxylase-related fusion polypeptides for the production of omega-hydroxylated fatty acid derivatives.

Omega-hydroxylase-related fusion polypeptide variants with improved properties

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Hemipteran, Lepidopteran, Coleopteran, Dipteran, fungal, and nematode pest populations and for producing compositions with insecticidal activity.

Insecticidal proteins and methods for their use

The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.

Methods of producing omega-hydroxylated fatty acid derivatives

Method for producing a chemical with synthetic microorganism encoding a monooxygenase

Omega-hydroxylase-related fusion polypeptides with improved properties

The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.

Car enzymes and improved production of fatty alcohols

Identification and use of proteins fluorescently labeled and that undergo a change in fluorescence index upon binding bilirubin are described. Probes are disclosed which are labeled at a cysteine or lysine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for determination of unbound bilirubin levels in a fluid sample.

Development and use of fluorescent probes of unbound bilirubin

Methods and compositions for the oxidation of short alkanes by engineered microorganisms expressing recombinant enzymes is described, along with methods of use.

Growing community of inventors

San Diego, CA, United States of America

Baolong Zhu