Conopco, Inc.

Unilever Plc

Unilever, N.v.

Hindustan Unilever Limited

Unilever IP Holdings B.v.

Unilever Global IP Limited

Balu Kunjupillai

Amitabha Majumdar

Ashish Anant Vaidya

Anita Damodaran

Mohan Vijaykumar Chavan

Vijay Ramchandra Gadgil

Khushbu Agarwal

Abhishek Rastogi

Rezwan Shariff

Manoj Kumar Joshi

Nilmoni Ghosh

Rajkumar Perumal

The present invention relates to a topical composition comprising from 0.001 to 10% by weight a compound of formula (I), i.e. N-cyclopropyl nicotinamide, that provides improved antimicrobial effect through generation of antimicrobial peptides when applied to an external surface of the human body. A combination of compound of formula I and at least one ingredient selected from niacinamide, picolinamide and iso-nicotinamide triggers generation of AMPs in a synergistic way.

Topical composition

The present invention is in the field of personal care compositions; in particular skin lightening compositions. It is believed that niacinamide reduces the melanosome transfer from melanocytes to keratinocytes thereby bringing about skin lightening. However, niacinamide is known to have little or no effect directly on the melanin content in the melanocytes. Thus a composition with multiple modes of action, that combines the reduction of melanosome transfer and the reduction of melanin content in the melanocytes remains to be desired. It is therefore an object of the present invention to provide a composition with synergistic amounts of picolinamide and niacinamide, providing improved melanosome transfer inhibition. It has been found that a synergistic skin lightening effect is obtained when niacinamide is combined with its isomer, picolinamide.

Skin lightening composition

The present invention relates to a broad spectrum stable sunscreen molecule having the general structure (Formula) where 'X' is an organic sunscreen belonging to the UVA class and 'Y' is an organic sunscreen belonging to UVB class or vice-versa. The invention also relates to a stable sunscreen composition comprising the inventive sunscreen molecule, a UV-B organic sunscreen and a cosmetically acceptable base. The invention also relates to a method of providing UV protection to the sun-exposed parts of human or animal body comprising the step of applying the above composition. 

Sunscreen molecule and compositions thereof

Growing community of inventors

Nagapattinam, India

Balu Kunjupillai