Solvias Ag

Balamurugan Ramalingam

Felix Spindler

Benoit Pugin

Andreas Pfaltz

Benoît Pugin

Yann Ribourdouille

Xiangdong Feng

Ligands of the formula (I) secondary phosphine-Q-P(&#x2550;O)HR(I) in the form of mixtures of diastereomers or pure diastereomers, in which secondary phosphine is a secondary phosphine group with hydrocarbon radicals or heterohydrocarbon radicals as substituents; Q is a bivalent bisaryl or bisheteroaryl radical with an axial chiral centre to which the two phosphorus atoms are bonded in the ortho positions to the bisaryl or bisheteroaryl bridge bond, or Q is a bivalent ferrocenyl radical with a planar chiral centre or without a planar chiral centre, to which the phosphorus atom of the secondary phosphine is bonded directly or via a C-C-carbon chain to a cyclopentadienyl ring, the &#x2014;P*(&#x2550;O)HRgroup is bonded either on the same cyclopentadienyl ring in ortho position to the bonded secondary phosphine or on the other cyclopentadienyl ring; P* is a chiral phosphorus atom, and Ris a hydrocarbon radical, a heterohydrocarbon radical or a ferrocenyl radical, where Ris a ferrocenyl radical with a planar chiral centre when Q is a ferrocenyl radical without a planar chiral centre. Metal complexes of these ligands are homogeneous catalysts for asymmetric addition reactions, particularly hydrogenations.

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Jeyankondam, India

Balamurugan Ramalingam