Gannex Pharma Co., Ltd.

Jiangsu Kanion Pharmaceutical Co., Ltd.

Bailing Yang

Jian Li

Shuhui Chen

Peng Li

Jinzi Jason Wu

Bin Liang

Haiying He

Wang Shen

Wei Xiao

Zhenzhong Wang

Ning Li

Zongbin Li

Fei Hao

Zheng Kuan Wang

Zheng Wang

A method for preparing the cyclic phosphonate compound of Formula I is described. The method significantly improves the stereoselectivity of the compound with the required configuration.

Preparation method of a cyclic phosphonate compound

The present invention discloses a salt form, crystal form and intermediate of the compound 1, and preparation method thereof. 

Salt form and crystal form of 1,2,5-thiadiazolidin-1,1-dioxide, preparation method thereof and intermediate

Disclosed is a novel anti-enterovirus 71 (EV71) 1,2,5-thiadiazolidine-1,1-dioxide derivative or a pharmaceutically acceptable salt thereof, and specifically, a compound represented by formula (II) or a pharmaceutically acceptable salt thereof. 

Anti-enterovirus 71 thiadiazolidine derivative

Growing community of inventors

Shanghai, China

Bailing Yang