Abbott Laboratories Corporation

Bailin Tu

Robert N Ziemann

Joan D Tyner

Susan E Brophy

David J Hawksworth

Bryan C Tieman

Larry G Birkenmeyer

Robert William Siegel

Mary S Pinkus

Carol S Ramsay

Anthony Scott Muerhoff

Dinesh O Shah

Barry Lee Dowell

Dagang Huang

Cheng Zhao

Carolyn J Strobel

Philip M Hemken

Michael White

Frank C Grenier

James W Scheffel

Robin A Gutierrez

Ryan F Workman

Lowell J Tyner, Legal Representative

Jeffrey M Werneke

Suresh M Desai

Saul A Datwyler

Qiaoqiao Ruan

Sergey Y Tetin

Jonathan Grote

Salman Ali

Hina N Syed

Edward T Olejniczak

Jessie W Shih

Kevin R Rupprecht

Dominick L Pucci

Sharmila Manoj

Zhiguang Yu

Tracey D Rae

Jan Schultess

Ryan M Bonn

David C Sogin

Don M Laird

Lianli Chi

Christian Beckert

Joan D(deceased) Tyner

Barry L Dowell

Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.

Anti-GP73 monoclonal antibodies and methods of obtaining the same

The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of

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The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.

Antibodies to troponin I and methods of use thereof

Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin Dand 25-hydroxy vitamin Din a test sample.

Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use

The present invention relates to antibodies specific for glycosylated mammalian NGAL, and to methods of making and using such antibodies.

Antibodies that bind to mammalian NGAL and uses thereof

The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.

PlGF-1 assay and kits and components thereof

Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.

Recombinant antibodies against hepatitis C virus and methods of obtaining and using same

A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.1; a method of obtaining from urine a composition comprising a plurality of isoforms of NGAL, which method comprises enriching NGAL in urine without separating molecules based on charge; a method of obtaining from recombinant CHO cells a composition comprising a plurality of isoforms of NGAL, which method comprises enriching NGAL in a composition without separating molecules based on charge; and a method of analyzing NGAL isoforms enriched from urine or recombinant CHO cells comprising analyzing an enriched composition comprising NGAL isoforms by two-dimensional electrophoresis and Western blot.

Neutrophil gelatinase-associated lipocalin (NGAL) protein isoforms enriched from urine and recombinant chinese hamster ovary (CHO) cells and related compositions, antibodies, and methods of enrichment, analysis and use

The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.

Human BNP immunospecific antibodies

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Libertyville, IL, United States of America

Bailin Tu