Iowa State University Research Foundation, Inc.

Boehringer Ingelheim Vetmedica Gmbh

Other

Bailey Arruda

Luis Gabriel Gimenez-Lirola

Arun V Iyer

Abby Rae Patterson

Troy James Kaiser

Joseph Ralph Hermann

Kent Jay Schwartz

Pablo E Pineyro Pineiro

Dave Michael Anstrom

Eric Martin Vaughn

Luis Alejandro Hernandez

Joseph Gilbert Victoria

Callie Ann Visek

Lea Ann Hobbs

Drew Robert Magstadt

Paulo Henrique Elias Arruda

Qi Chen

Phillip Gauger

Jianqiang Zhang

John K Jackman

Kevin J Brownfield

Maria J Clavijo

Arun Iyer

Abby Patterson

The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.

Porcine circovirus type 3 (PCV3) vaccines, and production and uses thereof

Porcine Circovirus Type 3 (PCV3) vaccines, and production and uses thereof

The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.

Chimericpolyprotein for vaccines and diagnostics

A tracheal sampling device is used to collect or acquire cells from an animal, such as at or near the tracheo-bronchial or larynx of an animal. The device includes a flexible and elongated shaft or stem, and a collection member at a distal end of the device. The collection member could be a swab or other member to best collect mucus. The device is used by inserting the collection end into an animal to position the collection member at or near the cell collection site, which may be in or around the larynx. The collection member is removed after collecting cells, which can be reviewed, tested, or otherwise managed to determine the presence of a disease or other bacteria. The length of the shaft or stem allows for optimal positioning of the swab in a variety of animal species and ages. The device can be disposed after each use.

Tracheo-bronchial sampling device

The present invention relates to the use of an immunogenic composition that comprises a porcinetype 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.

The present invention is directed to novel polynucleotides, polypeptides, and polyproteins ofsurface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective againstinfections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.

Chimeric M. hyorhinis polyprotein for vaccines and diagnostics

The present invention is directed to novel nucleotide and amino acid sequences of Porcine('PSV'), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PSV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full-length PSV genomes that can replicate efficiently in host animals and tissue culture.

Attenuated porcine sapelovirus strain and immunogenic compositions therefrom

The present invention relates to a vaccine for protecting a piglet against diseases associated with a novel pestivirus. The vaccine commonly includes a pestivirus antigen and, optionally an adjuvant. Methods for protecting pigs against diseases associated with pestivirus, including but not limited to congenital tremors and methods of producing the pestivirus vaccine are also provided.

Pestivirus vaccines for congenital tremors

The present invention relates to a vaccine for protecting a piglet against diseases associated with a novel. The vaccine commonly includes aantigen and, optionally an adjuvant. Methods for protecting pigs against diseases associated with, including but not limited to congenital tremors and methods of producing thevaccine are also provided.

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Ames, IA, United States of America

Bailey Arruda